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    DAL2 allantoicase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854847, updated on 17-May-2024

    Summary

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    Gene symbol
    DAL2
    Gene description
    allantoicase
    Primary source
    FungiDB:YIR029W
    Locus tag
    YIR029W
    See related
    SGD:S000001468; AllianceGenome:SGD:S000001468; VEuPathDB:YIR029W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ALC1
    Summary
    Enables allantoicase activity. Involved in allantoin catabolic process. Orthologous to human ALLC (allantoicase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See DAL2 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (410807..411838)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene allantoinase Neighboring gene allantoin permease Neighboring gene Dcg1p Neighboring gene malate synthase DAL7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution. Xu Q, et al. Proteins, 2004 Aug 15. PMID 15229895
    2. Crystal structure of yeast allantoicase reveals a repeated jelly roll motif. Leulliot N, et al. J Biol Chem, 2004 May 28. PMID 15020593
    3. AtAAH encodes a protein with allantoate amidohydrolase activity from Arabidopsis thaliana. Todd CD, et al. Planta, 2006 Apr. PMID 16496096
    4. Sequences of two adjacent genes, one (DAL2) encoding allantoicase and another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces cerevisiae. Yoo HS, et al. Gene, 1991 Jul 31. PMID 1916277
    5. Impact of chromosomal inversions on the yeast DAL cluster. Naseeb S, et al. PLoS One, 2012. PMID 22916115, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables allantoicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables allantoicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables allantoicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in allantoin catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in allantoin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in allantoin catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in purine nucleobase metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    allantoicase
    NP_012295.1
    • Allantoicase; converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      410807..411838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179551.1 → NP_012295.1  TPA: allantoicase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012295.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVW0, P25335
      UniProtKB/TrEMBL
      A0A6A5Q341, A6ZVU9, C7GLS7, C8ZAT0, G2WFV7, N1P1T4
      Conserved Domains (1) summary
      cl27253
      Location:1 → 343
      Alc; Allantoicase [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25335.1

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