rap1gapa RAP1 GTPase activating protein a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rap1gapaprovided by ZNC
Official Full Name: RAP1 GTPase activating protein aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-080402-9
See related: Ensembl:ENSDARG00000056554 AllianceGenome:ZFIN:ZDB-GENE-080402-9
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rap1gap; zgc:175180
Summary: Predicted to enable GTPase activator activity. Predicted to act upstream of or within regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm. Orthologous to human RAP1GAP (RAP1 GTPase activating protein). [provided by Alliance of Genome Resources, Oct 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (22311580..22425257)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (22385029..22498706)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

a proper level of Rap1 is crucial for heart morphogenesis and function.
Title: Suppression of Rap1 impairs cardiac myofibrils and conduction system in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of small GTPase mediated signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: rap1 GTPase-activating protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.