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    il13ra2.S interleukin 13 receptor subunit alpha 2 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 495398, updated on 4-Nov-2024

    Summary

    Official Symbol
    il13ra2.S
    Official Full Name
    interleukin 13 receptor subunit alpha 2 S homeolog
    Primary source
    Xenbase:XB-GENE-866197
    Locus tag
    XELAEV_18042296mg
    See related
    EnsemblRapid:ENSXLAG00005010358 AllianceGenome:Xenbase:XB-GENE-866197
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    il13ra2
    Summary
    Predicted to enable cytokine receptor activity. Predicted to act upstream of or within cytokine-mediated signaling pathway. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in breast cancer and pancreatic cancer. Orthologous to human IL13RA2 (interleukin 13 receptor subunit alpha 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See il13ra2.S in Genome Data Viewer
    Location:
    chromosome: 8S
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (75229143..75262735, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (72875097..72908700, complement)

    Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 9b S homeolog Neighboring gene 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog Neighboring gene plastin 3 S homeolog Neighboring gene protein FAM162A

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    interleukin 13 receptor subunit alpha 2 S homeolog
    Names
    interleukin 13 receptor, alpha 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001095057.1NP_001088526.1  interleukin 13 receptor subunit alpha 2 S homeolog

      See identical proteins and their annotated locations for NP_001088526.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084869
      UniProtKB/TrEMBL
      Q5U516
      Related
      ENSXLAP00005030542.1, ENSXLAT00005031299.1
      Conserved Domains (2) summary
      smart00060
      Location:245303
      FN3; Fibronectin type 3 domain
      pfam09240
      Location:150242
      IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      75229143..75262735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018232079.1XP_018087568.1  interleukin 13 receptor subunit alpha 2 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A1L8F366, A0A974C400
      Related
      ENSXLAP00005030554.1, ENSXLAT00005031311.1
    2. XM_041574291.1XP_041430225.1  interleukin 13 receptor subunit alpha 2 S homeolog isoform X2

      UniProtKB/TrEMBL
      A0A8J1LNF1
      Related
      ENSXLAP00005030548.1, ENSXLAT00005031305.1
      Conserved Domains (1) summary
      smart00060
      Location:245303
      FN3; Fibronectin type 3 domain