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    tbxas1.L thromboxane A synthase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 779365, updated on 4-Nov-2024

    Summary

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    Official Symbol
    tbxas1.L
    Official Full Name
    thromboxane A synthase 1 L homeolog
    Primary source
    Xenbase:XB-GENE-994328
    Locus tag
    XELAEV_18002508mg
    See related
    EnsemblRapid:ENSXLAG00005006566 AllianceGenome:Xenbase:XB-GENE-994328
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    txs; cyp5; thas; txas; cyp5a1; ghosal; tbxas1
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and steroid hydroxylase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tbxas1.L in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (7022913..7051327)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694822.1 (2095164..2122689)

    Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene KIAA1549 L homeolog Neighboring gene homeodomain interacting protein kinase 2 L homeolog Neighboring gene uncharacterized LOC108704350 Neighboring gene sperm-specific basic nuclear protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC68549

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables steroid hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    thromboxane A synthase 1, platelet
    Names
    thromboxane A synthase 1 (platelet)
    NP_001090452.1
    XP_041441225.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001096983.1 → NP_001090452.1  thromboxane A synthase 1, platelet

      See identical proteins and their annotated locations for NP_001090452.1

      Status: PROVISIONAL

      Source sequence(s)
      BC060001
      UniProtKB/TrEMBL
      Q6PAY3, Q6PCI4
      Related
      ENSXLAP00005019504.1, ENSXLAT00005019839.1
      Conserved Domains (1) summary
      pfam00067
      Location:45 → 532
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      7022913..7051327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041585291.1 → XP_041441225.1  thromboxane A synthase 1, platelet isoform X1

      UniProtKB/TrEMBL
      A0A8J1MJL3, Q6PCI4
      Conserved Domains (1) summary
      COG2124
      Location:84 → 535
      CypX; Cytochrome P450 [Secondary metabolites biosynthesis, transport and catabolism, Defense mechanisms]
    Nucleotide Protein Strain
    Heading Accession and Version

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