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    cxcr1.S C-X-C motif chemokine receptor 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398309, updated on 4-Nov-2024

    Summary

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    Official Symbol
    cxcr1.S
    Official Full Name
    C-X-C motif chemokine receptor 1 S homeolog
    Primary source
    Xenbase:XB-GENE-5756232
    Locus tag
    XELAEV_18046978mg
    See related
    EnsemblRapid:ENSXLAG00005013604 AllianceGenome:Xenbase:XB-GENE-5756232
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    cxcr1; cxcr2
    Summary
    Predicted to enable C-C chemokine binding activity; C-C chemokine receptor activity; and C-X-C chemokine receptor activity. Predicted to act upstream of or within several processes, including calcium-mediated signaling; neutrophil chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in external side of plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See cxcr1.S in Genome Data Viewer
    Location:
    chromosome: 9_10S
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (52242372..52249804, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (45583626..45585526, complement)

    Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene tensin 1 S homeolog Neighboring gene C-X-C chemokine receptor type 2-like Neighboring gene actin related protein 2/3 complex subunit 2 S homeolog Neighboring gene keratin 18, gene 3 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC86426

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables C-C chemokine binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables C-C chemokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables C-X-C chemokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-X-C motif chemokine receptor 1 S homeolog
    Names
    CXCR2 like protein
    chemokine (C-X-C motif) receptor 1 S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001088765.1 → NP_001082234.1  C-X-C motif chemokine receptor 1 S homeolog

      See identical proteins and their annotated locations for NP_001082234.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084427
      UniProtKB/TrEMBL
      A0A974BUI1, Q8QFR5
      Conserved Domains (1) summary
      cd15178
      Location:39 → 316
      7tmA_CXCR1_2; CXC chemokine receptor types 1 and 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      52242372..52249804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041577696.1 → XP_041433630.1  C-X-C motif chemokine receptor 1 S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A974BUI1, Q8QFR5
      Related
      ENSXLAP00005040107.1, ENSXLAT00005041030.1
      Conserved Domains (1) summary
      cd15178
      Location:39 → 316
      7tmA_CXCR1_2; CXC chemokine receptor types 1 and 2, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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