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    htatip2 HIV-1 Tat interactive protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 64605, updated on 2-Nov-2024

    Summary

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    Official Symbol
    htatip2provided by ZNC
    Official Full Name
    HIV-1 Tat interactive protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-001219-1
    See related
    Ensembl:ENSDARG00000028386 AllianceGenome:ZFIN:ZDB-GENE-001219-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tip30; fb15b04; wu:fb15b04
    Summary
    Predicted to be involved in import into nucleus. Predicted to act upstream of or within angiogenesis. Predicted to be located in nuclear envelope. Predicted to be active in cytoplasm. Orthologous to human HTATIP2 (HIV-1 Tat interactive protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See htatip2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (17096281..17103176)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (16844308..16851203)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496161 Neighboring gene developing brain homeobox 1a Neighboring gene uncharacterized LOC137496160 Neighboring gene protein arginine methyltransferase 3 Neighboring gene solute carrier family 6 member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. Desai S, et al. BMC Evol Biol, 2008 Jun 19. PMID 18565225, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    oxidoreductase HTATIP2
    Names
    tat-interacting protein 30 kDa
    NP_571756.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131681.2 → NP_571756.1  oxidoreductase HTATIP2

      See identical proteins and their annotated locations for NP_571756.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the functional protein
      Source sequence(s)
      CR786573, EH476941, EH550887
      UniProtKB/TrEMBL
      F6PBV1, Q4V932, Q90Z77
      Related
      ENSDARP00000037018.6, ENSDART00000035558.8
      Conserved Domains (2) summary
      cd05250
      Location:15 → 227
      CC3_like_SDR_a; CC3(TIP30)-like, atypical (a) SDRs
      COG0702
      Location:19 → 207
      YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]

    RNA

    1. NR_131978.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an additional internal segmaent compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      CR786573
      Related
      ENSDART00000140367.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      17096281..17103176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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