U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    tomm34 translocase of outer mitochondrial membrane 34 [ Danio rerio (zebrafish) ]

    Gene ID: 323361, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    tomm34provided by ZNC
    Official Full Name
    translocase of outer mitochondrial membrane 34provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2081
    See related
    Ensembl:ENSDARG00000001557 AllianceGenome:ZFIN:ZDB-GENE-030131-2081
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zC239J9.1; zgc:56645; wu:fb96b08
    Summary
    Predicted to enable heat shock protein binding activity. Predicted to be involved in protein targeting to mitochondrion. Predicted to be located in cytoplasm. Predicted to be active in cytosol and mitochondrion. Is expressed in alar plate midbrain region; myotome; optic tectum; optic vesicle; and retina. Orthologous to human TOMM34 (translocase of outer mitochondrial membrane 34). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See tomm34 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (52226682..52234912, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (52226683..52234913, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a Neighboring gene cytochrome c oxidase subunit 6C Neighboring gene zinc finger CCCH-type containing 10

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of the 14-3-3 β/α-A protein as a novel maternal peptidoglycan-binding protein that protects embryos of zebrafish against bacterial infections. Wang X, et al. Dev Comp Immunol, 2021 Jan. PMID 32931839
    2. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    3. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables heat shock protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    mitochondrial import receptor subunit TOM34

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199638.2 → NP_955932.2  mitochondrial import receptor subunit TOM34

      Status: VALIDATED

      Source sequence(s)
      BX465851, EB848928, EH519797
      UniProtKB/TrEMBL
      A0A8M1P9V8, Q6ZM24
      Related
      ENSDARP00000001240.7, ENSDART00000001803.8
      Conserved Domains (4) summary
      smart00028
      Location:226 → 257
      TPR; Tetratricopeptide repeats
      sd00006
      Location:191 → 218
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:258 → 291
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:191 → 254
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      52226682..52234912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools