U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rcn1 reticulocalbin 1, EF-hand calcium binding domain [ Danio rerio (zebrafish) ]

    Gene ID: 562671, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rcn1provided by ZNC
    Official Full Name
    reticulocalbin 1, EF-hand calcium binding domainprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080225-33
    See related
    Ensembl:ENSDARG00000070006 AllianceGenome:ZFIN:ZDB-GENE-080225-33
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7158588; wu:fa06h02
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including axial mesoderm; chordo neural hinge; epidermis; head; and pectoral fin. Orthologous to human RCN1 (reticulocalbin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rcn1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (15818903..15830161, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (15570892..15582358, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene myocyte enhancer factor 2ab Neighboring gene multiple C2 domains, transmembrane 2b Neighboring gene paired box 6b Neighboring gene elongator acetyltransferase complex subunit 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. Bhatia S, et al. Dev Biol, 2014 Mar 15. PMID 24440152
    2. Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence. Kleinjan DA, et al. PLoS Genet, 2008 Feb. PMID 18282108, Free PMC Article
    3. Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene. Feiner N, et al. Genome Biol Evol, 2014 Jun 19. PMID 24951566, Free PMC Article
    4. Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Navratilova P, et al. Dev Biol, 2009 Mar 15. PMID 19073165
    5. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    reticulocalbin-1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      15818903..15830161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_686046.9 → XP_691138.1  reticulocalbin-1

      UniProtKB/TrEMBL
      A0A8N7TEW4, F1R369
      Related
      ENSDARP00000093139.4, ENSDART00000102363.5
      Conserved Domains (3) summary
      cd00051
      Location:199 → 262
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:161 → 221
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:75 → 132
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools