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    terf1 telomeric repeat binding factor (NIMA-interacting) 1 [ Danio rerio (zebrafish) ]

    Gene ID: 566954, updated on 2-Nov-2024

    Summary

    Official Symbol
    terf1provided by ZNC
    Official Full Name
    telomeric repeat binding factor (NIMA-interacting) 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090612-2
    See related
    Ensembl:ENSDARG00000058710 AllianceGenome:ZFIN:ZDB-GENE-090612-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb74c04
    Summary
    Enables telomeric DNA binding activity. Predicted to be involved in negative regulation of telomeric D-loop disassembly and telomere maintenance via telomerase. Predicted to act upstream of or within telomere maintenance. Predicted to be located in chromosome, telomeric region and nucleus. Predicted to be part of nuclear telomere cap complex. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Orthologous to human TERF1 (telomeric repeat binding factor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See terf1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (13337216..13349525, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (13192794..13205072, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene si:ch211-171b20.3 Neighboring gene uncharacterized LOC137489216 Neighboring gene somatomedin B and thrombospondin type 1 domain containing Neighboring gene potassium voltage-gated channel subfamily B member 2b Neighboring gene uncharacterized LOC137489217 Neighboring gene transient receptor potential cation channel, subfamily A, member 1b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables double-stranded telomeric DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to telomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables telomeric DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of telomeric D-loop disassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within telomere maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in telomere maintenance via telomerase IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear telomere cap complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    telomeric repeat-binding factor 1
    Names
    telomeric repeat binding factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      13337216..13349525 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_690237.7XP_695329.7  telomeric repeat-binding factor 1

      Related
      ENSDARP00000118728.1, ENSDART00000134482.3