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    tlcd1 TLC domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 450051, updated on 2-Nov-2024

    Summary

    Official Symbol
    tlcd1provided by ZNC
    Official Full Name
    TLC domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-173
    See related
    Ensembl:ENSDARG00000002391 AllianceGenome:ZFIN:ZDB-GENE-041010-173
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101692
    Summary
    Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in hindbrain and spinal cord. Orthologous to human TLCD1 (TLC domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tlcd1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26080215..26089899, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26043520..26053204, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD42 Neighboring gene small nucleolar RNA SNORD42 Neighboring gene ribosomal protein L23a Neighboring gene NIPA like domain containing 4 Neighboring gene uncharacterized LOC103909466

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in membrane assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phospholipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in plasma membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of membrane lipid distribution IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    TLC domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006071.1NP_001006071.1  TLC domain-containing protein 1

      See identical proteins and their annotated locations for NP_001006071.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083250
      UniProtKB/TrEMBL
      Q5XJP8
      Related
      ENSDARP00000009170.6, ENSDART00000027848.7
      Conserved Domains (1) summary
      smart00724
      Location:45237
      TLC; TRAM, LAG1 and CLN8 homology domains

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      26080215..26089899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)