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    kifc1 kinesin family member C1 [ Danio rerio (zebrafish) ]

    Gene ID: 30453, updated on 2-Nov-2024

    Summary

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    Official Symbol
    kifc1provided by ZNC
    Official Full Name
    kinesin family member C1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000208-21
    See related
    Ensembl:ENSDARG00000001558 AllianceGenome:ZFIN:ZDB-GENE-000208-21
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    knsl2; fc27e02; fd14g02; wu:fc27e02; wu:fd14g02
    Summary
    Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement and mitotic spindle assembly. Predicted to be located in cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in head. Orthologous to human KIFC1 (kinesin family member C1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human all
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    Genomic context

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    See kifc1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (6990971..7000727)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7072052..7081597)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene flotillin 1a Neighboring gene zinc finger protein 384 a Neighboring gene zinc finger and BTB domain containing 22b Neighboring gene death-domain associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The C-terminal kinesin motor KIFC1 may participate in nuclear reshaping and flagellum formation during spermiogenesis of Larimichthys crocea. Zhang DD, et al. Fish Physiol Biochem, 2017 Oct. PMID 28534180
    2. Molecular cloning and characterization of KIFC1-like kinesin gene (es-KIFC1) in the testis of the Chinese mitten crab Eriocheir sinensis. Wang DH, et al. Comp Biochem Physiol A Mol Integr Physiol, 2010 Oct. PMID 20554056
    3. Identification of seven genes in the major histocompatibility complex class I region of the zebrafish. Sültmann H, et al. Scand J Immunol, 2000 Jun. PMID 10849368
    4. A contig map of the Mhc class I genomic region in the zebrafish reveals ancient synteny. Michalová V, et al. J Immunol, 2000 May 15. PMID 10799891
    5. Characterization of immune-matched hematopoietic transplantation in zebrafish. de Jong JL, et al. Blood, 2011 Apr 21. PMID 21346254, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC162386

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    kinesin-like protein KIFC1
    Names
    kinesin-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044954.2 → NP_001038419.1  kinesin-like protein KIFC1

      See identical proteins and their annotated locations for NP_001038419.1

      Status: VALIDATED

      Source sequence(s)
      FP102097
      UniProtKB/TrEMBL
      A0A8M2B6D9, A4QNZ0, Q1LUU7
      Related
      ENSDARP00000155080.1, ENSDART00000193566.1
      Conserved Domains (2) summary
      cd01366
      Location:271 → 610
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      cl25732
      Location:101 → 275
      SMC_N; RecF/RecN/SMC N terminal domain

    2. NM_131206.2 → NP_571281.2  kinesin-like protein KIFC1

      Status: VALIDATED

      Source sequence(s)
      FP102097
      UniProtKB/TrEMBL
      A0A8M2B6D9, A4QNZ0, Q1LUU7
      Related
      ENSDARP00000139775.1, ENSDART00000160482.2
      Conserved Domains (2) summary
      cd01366
      Location:271 → 610
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      cl25732
      Location:101 → 275
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      6990971..7000727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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