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    ostm1 osteoclastogenesis associated transmembrane protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100320445, updated on 10-Sep-2024

    Summary

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    Official Symbol
    ostm1provided by ZNC
    Official Full Name
    osteoclastogenesis associated transmembrane protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-270
    See related
    Ensembl:ENSDARG00000069808 AllianceGenome:ZFIN:ZDB-GENE-081104-270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa04a09; wu:fa04a09; si:ch73-257c13.3
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 5. Orthologous to human OSTM1 (osteoclastogenesis associated transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (32478107..32491036)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (32575238..32584956)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 3 Neighboring gene nuclear receptor subfamily 2, group E, member 1 Neighboring gene si:ch73-257c13.2 Neighboring gene SEC63 homolog, protein translocation regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking. Pandruvada SN, et al. Mol Cell Biol, 2016 Feb 1. PMID 26598607, Free PMC Article
    2. Stat5b Regulates Sexually Dimorphic Gene Expression in Zebrafish Liver. Huang P, et al. Front Physiol, 2018. PMID 29904357, Free PMC Article
    3. FOXO genes in channel catfish and their response after bacterial infection. Gao L, et al. Dev Comp Immunol, 2019 Aug. PMID 30905685
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    osteopetrosis-associated transmembrane protein 1
    Names
    osteopetrosis associated transmembrane protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386310.1 → NP_001373239.1  osteopetrosis-associated transmembrane protein 1

      Status: VALIDATED

      Source sequence(s)
      CU207298
      UniProtKB/TrEMBL
      A0A8M1RHW9
      Related
      ENSDARP00000119392.2, ENSDART00000145269.3
      Conserved Domains (1) summary
      pfam09777
      Location:73 → 295
      OSTMP1; Osteopetrosis-associated transmembrane protein 1 precursor

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      32478107..32491036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002665742.6 → XP_002665788.2  osteopetrosis-associated transmembrane protein 1

      Conserved Domains (1) summary
      pfam09777
      Location:73 → 295
      OSTMP1; Osteopetrosis-associated transmembrane protein 1 precursor
    Nucleotide Protein Strain
    Heading Accession and Version

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