hmgb3a high mobility group box 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hmgb3aprovided by ZNC
Official Full Name: high mobility group box 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050428-1
See related: Ensembl:ENSDARG00000056725 AllianceGenome:ZFIN:ZDB-GENE-050428-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb17a03; wu:fk52f12; zgc:162415
Summary: Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including axis; intermediate cell mass of mesoderm; mesoderm; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (25913225..25918281)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (25642032..25647088)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk52f12.x1 (e-PCR)
- UniSTS:201125

fb17a03.y1 (e-PCR)
- UniSTS:190203

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA binding, bending	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: high mobility group protein B3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001122836.1 → NP_001116308.1 high mobility group protein B3a

Status: PROVISIONAL

Source sequence(s)

BX005022

UniProtKB/TrEMBL

A0A8N7UYU2, F1QGP8

Related

ENSDARP00000111817.2, ENSDART00000129924.4

Conserved Domains (2) summary

pfam00505
Location:92 → 159

HMG_box; HMG (high mobility group) box

pfam09011
Location:7 → 78

HMG_box_2; HMG-box domain