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    gra granulito [ Danio rerio (zebrafish) ]

    Gene ID: 561889, updated on 12-Sep-2024

    Summary

    Official Symbol
    graprovided by ZNC
    Official Full Name
    granulitoprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081022-203
    See related
    Ensembl:ENSDARG00000078754 AllianceGenome:ZFIN:ZDB-GENE-081022-203
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:195256; zgc:195266
    Summary
    Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to act upstream of or within negative regulation of translation. Located in P granule. Is expressed in blastomere and primordial germ cell. Orthologous to human C8orf88 (chromosome 8 open reading frame 88). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See gra in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (16222394..16226220, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (16314417..16318243, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene stathmin 2a Neighboring gene uridine phosphorylase 1 Neighboring gene RNA binding motif protein 12Bb Neighboring gene uncharacterized LOC110438014

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables eukaryotic initiation factor 4E binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables eukaryotic initiation factor 4E binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in P granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein C8orf88 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100948.2NP_001094418.2  uncharacterized protein C8orf88 homolog

      See identical proteins and their annotated locations for NP_001094418.2

      Status: VALIDATED

      Source sequence(s)
      BX321920, EH550198
      UniProtKB/TrEMBL
      B3DKF4, B3DKG4, F6NNX3
      Related
      ENSDARP00000098356.2, ENSDART00000108965.4
      Conserved Domains (1) summary
      pfam05456
      Location:84120
      eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      16222394..16226220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)