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    THO7 Tho complex subunit 7/Mft1p [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821174, updated on 18-Sep-2024

    Summary

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    Official Symbol
    THO7
    Official Full Name
    Tho complex subunit 7/Mft1p
    Primary source
    TAIR:AT3G02950
    Locus tag
    AT3G02950
    See related
    Araport:AT3G02950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTHO7; F13E7.10; F13E7_10
    Summary
    Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
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    Genomic context

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    See THO7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (665223..666922, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene weak chloroplast movement under blue light protein (DUF827) Neighboring gene myb domain protein 107 Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene uncharacterized protein Neighboring gene EXORDIUM like 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Yelina NE, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634427, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337451.1
    NM_111165.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of THO complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of THO complex part of transcription export complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tho complex subunit 7/Mft1p
    NP_566189.1
    • THO7; CONTAINS InterPro DOMAIN/s: Tho complex subunit 7 (InterPro:IPR018018), Tho complex subunit 7/Mft1p (InterPro:IPR008501); BEST Arabidopsis thaliana protein match is: Tho complex subunit 7/Mft1p (TAIR:AT5G16790.1); Has 2509 Blast hits to 2230 proteins in 391 species: Archae - 54; Bacteria - 255; Metazoa - 1226; Fungi - 237; Plants - 121; Viruses - 25; Other Eukaryotes - 591 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      665223..666922 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111165.4 → NP_566189.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566189.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M8T6
      UniProtKB/TrEMBL
      A0A178VDN6, A0A5S9X8L5
      Conserved Domains (1) summary
      pfam05615
      Location:29 → 166
      THOC7; Tho complex subunit 7

    2. NM_001337451.1 → NP_001327695.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M8T6
      UniProtKB/TrEMBL
      A0A178VDN6, A0A5S9X8L5
      Conserved Domains (1) summary
      pfam05615
      Location:29 → 166
      THOC7; Tho complex subunit 7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8T6.1

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