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    CYTOR cytoskeleton regulator RNA [ Homo sapiens (human) ]

    Gene ID: 112597, updated on 24-Sep-2024

    Summary

    Official Symbol
    CYTORprovided by HGNC
    Official Full Name
    cytoskeleton regulator RNAprovided by HGNC
    Primary source
    HGNC:HGNC:28717
    See related
    Ensembl:ENSG00000222041 AllianceGenome:HGNC:28717
    Gene type
    ncRNA
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C2orf59; LINC00152; NCRNA00152
    Summary
    This gene produces a long non-coding RNA that is overexpressed in cancer cells and promotes cell proliferation and epithelial-mesenchymal transition. This RNA may bind enhancer of zeste homolog 2 and participate in the transcriptional silencing of tumor suppressor genes. It may act as a sponge for microRNAs. Alternatively spliced variants have been observed. [provided by RefSeq, Dec 2017]
    Expression
    Broad expression in spleen (RPKM 10.4), bone marrow (RPKM 9.5) and 22 other tissues See more
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    Genomic context

    See CYTOR in Genome Data Viewer
    Location:
    2p11.2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (87455427..87521518)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (87467522..87533550)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (87754946..87821037)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124907854 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:91757725-91758235 Neighboring gene uncharacterized LOC105377635 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87581544-87582388 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87582389-87583233 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87623699-87624202 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87624203-87624704 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87633283-87633789 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87633790-87634295 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87641303-87641844 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87641845-87642385 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87642477-87643119 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87643120-87643761 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87643890-87644537 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87645185-87645831 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87644538-87645184 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87645832-87646477 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:87720936-87721436 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87647813-87648776 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87648777-87649739 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87724395-87725207 Neighboring gene long intergenic non-protein coding RNA 1943 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:87756227-87756812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:87762086-87762942 Neighboring gene uncharacterized LOC124906032 Neighboring gene NK cell activity associated lncRNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:87826545-87827046 Neighboring gene uncharacterized LOC107985909 Neighboring gene platelet activating factor acetylhydrolase 1b regulatory subunit 1 pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • long intergenic non-protein coding RNA 152

    Clone Names

    • MGC4677, MGC17532, MGC88182, AC133644.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024204.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      BC009508, BC073906, BG198684, HY175246
      Related
      ENST00000414584.1
    2. NR_024205.3 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC133644
    3. NR_024206.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      BC009508, BG198684, HY175246
      Related
      ENST00000331944.10
    4. NR_146460.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      BG198684, CD640509
      Related
      ENST00000437561.2
    5. NR_146461.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC133644
      Related
      ENST00000644577.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      87455427..87521518
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      87467522..87533550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)