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    Adgrl2 adhesion G protein-coupled receptor L2 [ Mus musculus (house mouse) ]

    Gene ID: 99633, updated on 2-Nov-2024

    Summary

    Official Symbol
    Adgrl2provided by MGI
    Official Full Name
    adhesion G protein-coupled receptor L2provided by MGI
    Primary source
    MGI:MGI:2139714
    See related
    Ensembl:ENSMUSG00000028184 AllianceGenome:MGI:2139714
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lec1; Gm619; Lphh1; Lphn2; CIRL-2; mKIAA0786
    Summary
    Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Involved in synapse organization. Acts upstream of or within positive regulation of synapse assembly and response to bacterium. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in central nervous system; future brain; and heart. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 41.1), CNS E14 (RPKM 39.9) and 20 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Adgrl2 in Genome Data Viewer
    Location:
    3 H3; 3 74.1 cM
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (148521491..149150832, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (148815586..148989096, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09250 Neighboring gene predicted gene, 29836 Neighboring gene STARR-seq mESC enhancer starr_09251 Neighboring gene predicted gene, 23131 Neighboring gene STARR-seq mESC enhancer starr_09252 Neighboring gene STARR-positive B cell enhancer mm9_chr3:148154297-148154597 Neighboring gene STARR-seq mESC enhancer starr_09253 Neighboring gene STARR-positive B cell enhancer mm9_chr3:148358491-148358791 Neighboring gene STARR-seq mESC enhancer starr_09254 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:148515580-148515781 Neighboring gene STARR-seq mESC enhancer starr_09255 Neighboring gene STARR-seq mESC enhancer starr_09256 Neighboring gene STARR-seq mESC enhancer starr_09257 Neighboring gene predicted gene, 30827 Neighboring gene STARR-seq mESC enhancer starr_09259 Neighboring gene STARR-seq mESC enhancer starr_09260 Neighboring gene predicted gene, 25127 Neighboring gene predicted gene, 30575 Neighboring gene STARR-seq mESC enhancer starr_09264 Neighboring gene STARR-seq mESC enhancer starr_09265 Neighboring gene STARR-positive B cell enhancer ABC_E337 Neighboring gene predicted gene 10287 Neighboring gene STARR-positive B cell enhancer mm9_chr3:149002145-149002445 Neighboring gene predicted gene, 57703 Neighboring gene predicted gene 1653 Neighboring gene RIKEN cDNA A630039O03 gene Neighboring gene STARR-positive B cell enhancer mm9_chr3:149073444-149073744 Neighboring gene STARR-positive B cell enhancer mm9_chr3:149108487-149108788 Neighboring gene predicted gene, 26468 Neighboring gene predicted gene 5149 Neighboring gene STARR-seq mESC enhancer starr_09268 Neighboring gene STARR-seq mESC enhancer starr_09269 Neighboring gene predicted gene, 31121 Neighboring gene STARR-seq mESC enhancer starr_09270 Neighboring gene predicted gene, 31244

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (7)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC38872

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynaptic membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    adhesion G protein-coupled receptor L2
    Names
    G protein coupled receptor Lec1
    calcium-independent alpha-latrotoxin receptor 2
    calcium-independent alpha-latrotoxin receptor homolog 2
    latrophilin 1
    latrophilin-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081298.2NP_001074767.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001074767.1

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      Consensus CDS
      CCDS80059.1
      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      UniProtKB/TrEMBL
      A0A0G2JGM8
      Related
      ENSMUSP00000143626.2, ENSMUST00000197567.5
      Conserved Domains (8) summary
      smart00303
      Location:788840
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:469533
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11281487
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:542764
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:850875
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:142398
      OLF; Olfactomedin-like domain
      cl28897
      Location:8491129
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. NM_001405986.1NP_001392915.1  adhesion G protein-coupled receptor L2 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    3. NM_001405987.1NP_001392916.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      Related
      ENSMUSP00000142347.2, ENSMUST00000198779.5
    4. NM_001405988.1NP_001392917.1  adhesion G protein-coupled receptor L2 isoform 19 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    5. NM_001405989.1NP_001392918.1  adhesion G protein-coupled receptor L2 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    6. NM_001405990.1NP_001392919.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    7. NM_001405991.1NP_001392920.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    8. NM_001405992.1NP_001392921.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    9. NM_001405993.1NP_001392922.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      Related
      ENSMUSP00000143444.2, ENSMUST00000195988.5
    10. NM_001405994.1NP_001392923.1  adhesion G protein-coupled receptor L2 isoform 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    11. NM_001405995.1NP_001392924.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      UniProtKB/TrEMBL
      A0A0G2JDE3
    12. NM_001405996.1NP_001392925.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      UniProtKB/TrEMBL
      A0A0G2JDE3
    13. NM_001405997.1NP_001392926.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      UniProtKB/TrEMBL
      A0A0G2JDE3
      Related
      ENSMUSP00000142336.2, ENSMUST00000200543.5
    14. NM_001405998.1NP_001392927.1  adhesion G protein-coupled receptor L2 isoform 9 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    15. NM_001405999.1NP_001392928.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    16. NM_001406000.1NP_001392929.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    17. NM_001406001.1NP_001392930.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    18. NM_001406002.1NP_001392931.1  adhesion G protein-coupled receptor L2 isoform 18 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    19. NM_001406003.1NP_001392932.1  adhesion G protein-coupled receptor L2 isoform 11 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      Related
      ENSMUSP00000143320.2, ENSMUST00000199750.5
    20. NM_001406004.1NP_001392933.1  adhesion G protein-coupled receptor L2 isoform 12 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    21. NM_001406005.1NP_001392934.1  adhesion G protein-coupled receptor L2 isoform 13 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    22. NM_001406006.1NP_001392935.1  adhesion G protein-coupled receptor L2 isoform 14 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    23. NM_001406007.1NP_001392936.1  adhesion G protein-coupled receptor L2 isoform 15 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    24. NM_001406008.1NP_001392937.1  adhesion G protein-coupled receptor L2 isoform 16 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    25. NM_001406009.1NP_001392938.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    26. NM_001406010.1NP_001392939.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
    27. NM_001406011.1NP_001392940.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113315, AC114679, AC138591
      Related
      ENSMUSP00000143788.2, ENSMUST00000196526.5
    28. NM_001406018.1NP_001392947.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC110553, AC113315, AC114679, AC115737, AC138591
    29. NM_001406019.1NP_001392948.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

      Status: VALIDATED

      Source sequence(s)
      AC110553, AC113315, AC114679, AC115737, AC138591, AC161434
      UniProtKB/TrEMBL
      A0A0G2JDE3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      148521491..149150832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163465.1XP_036019358.1  adhesion G protein-coupled receptor L2 isoform X28

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:10871155
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321088
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. XM_036163464.1XP_036019357.1  adhesion G protein-coupled receptor L2 isoform X28

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:10871155
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321088
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    3. XM_036163459.1XP_036019352.1  adhesion G protein-coupled receptor L2 isoform X23

      UniProtKB/TrEMBL
      A0A0G2JDF4
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641312
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    4. XM_036163477.1XP_036019370.1  adhesion G protein-coupled receptor L2 isoform X40

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641061
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    5. XM_036163462.1XP_036019355.1  adhesion G protein-coupled receptor L2 isoform X26

      UniProtKB/TrEMBL
      A0A0G2JG66
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641280
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    6. XM_036163475.1XP_036019368.1  adhesion G protein-coupled receptor L2 isoform X38

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641072
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    7. XM_036163471.1XP_036019364.1  adhesion G protein-coupled receptor L2 isoform X34

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9791087
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709980
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    8. XM_036163461.1XP_036019354.1  adhesion G protein-coupled receptor L2 isoform X25

      UniProtKB/TrEMBL
      A0A0G2JG66
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881293
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    9. XM_036163460.1XP_036019353.1  adhesion G protein-coupled receptor L2 isoform X24

      UniProtKB/TrEMBL
      A0A0G2JG66
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881304
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    10. XM_036163478.1XP_036019371.1  adhesion G protein-coupled receptor L2 isoform X41

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881054
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    11. XM_036163470.1XP_036019363.1  adhesion G protein-coupled receptor L2 isoform X33

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881096
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    12. XM_036163456.1XP_036019349.1  adhesion G protein-coupled receptor L2 isoform X20

      UniProtKB/TrEMBL
      A0A0G2JDF4
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641329
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    13. XM_036163457.1XP_036019350.1  adhesion G protein-coupled receptor L2 isoform X21

      UniProtKB/TrEMBL
      A0A0G2JFF5
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9791327
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709980
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    14. XM_036163455.1XP_036019348.1  adhesion G protein-coupled receptor L2 isoform X19

      UniProtKB/TrEMBL
      A0A0G2JFF5
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881336
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    15. XM_036163439.1XP_036019332.1  adhesion G protein-coupled receptor L2 isoform X2

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (8) summary
      smart00303
      Location:784836
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11241489
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538760
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:846871
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8451125
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    16. XM_036163447.1XP_036019340.1  adhesion G protein-coupled receptor L2 isoform X12

      UniProtKB/TrEMBL
      A0A0G2JG66
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11021407
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321103
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    17. XM_036163443.1XP_036019336.1  adhesion G protein-coupled receptor L2 isoform X7

      UniProtKB/TrEMBL
      A0A0G2JDF4
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:10871452
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321088
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    18. XM_036163452.1XP_036019345.1  adhesion G protein-coupled receptor L2 isoform X16

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881353
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    19. XM_006502433.5XP_006502496.1  adhesion G protein-coupled receptor L2 isoform X7

      UniProtKB/TrEMBL
      A0A0G2JDF4
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:10871452
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321088
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    20. XM_036163479.1XP_036019372.1  adhesion G protein-coupled receptor L2 isoform X42

      Conserved Domains (5) summary
      smart00303
      Location:157209
      GPS; G-protein-coupled receptor proteolytic site domain
      pfam02354
      Location:497862
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:1133
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:219244
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:218498
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    21. XM_036163446.1XP_036019339.1  adhesion G protein-coupled receptor L2 isoform X11

      UniProtKB/TrEMBL
      A0A0G2JFV3
      Conserved Domains (8) summary
      smart00303
      Location:705757
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:399463
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:10451410
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:472681
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:767792
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:7661046
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    22. XM_006502424.5XP_006502487.1  adhesion G protein-coupled receptor L2 isoform X2

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (8) summary
      smart00303
      Location:784836
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11241489
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538760
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:846871
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8451125
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    23. XM_036163438.1XP_036019331.1  adhesion G protein-coupled receptor L2 isoform X1

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Related
      ENSMUSP00000142405.2, ENSMUST00000199238.5
      Conserved Domains (8) summary
      smart00303
      Location:789841
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:470534
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11291494
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:543765
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:851876
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:143399
      OLF; Olfactomedin-like domain
      cl28897
      Location:8501130
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    24. XM_036163458.1XP_036019351.1  adhesion G protein-coupled receptor L2 isoform X22

      UniProtKB/TrEMBL
      A0A0G2JDF4
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641318
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    25. XM_036163454.1XP_036019347.1  adhesion G protein-coupled receptor L2 isoform X18

      UniProtKB/TrEMBL
      A0A0G2JFF5
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881342
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    26. XM_036163451.1XP_036019344.1  adhesion G protein-coupled receptor L2 isoform X16

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881353
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    27. XM_030252947.1XP_030108807.1  adhesion G protein-coupled receptor L2 isoform X15

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (7) summary
      smart00303
      Location:661713
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      cd14964
      Location:723748
      7tm_GPCRs; TM helix 1 [structural motif]
      pfam02354
      Location:10021366
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415637
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:7221002
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    28. XM_036163440.1XP_036019333.1  adhesion G protein-coupled receptor L2 isoform X3

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11111476
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321112
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    29. XM_030252944.2XP_030108804.1  adhesion G protein-coupled receptor L2 isoform X3

      UniProtKB/Swiss-Prot
      E9Q6C7, Q8BM90, Q8JZZ7
      Conserved Domains (8) summary
      smart00303
      Location:771823
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:465529
      HormR; Domain present in hormone receptors
      pfam02140
      Location:49129
      Gal_Lectin; Galactose binding lectin domain
      pfam02354
      Location:11111476
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:538747
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:833858
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:138394
      OLF; Olfactomedin-like domain
      cl28897
      Location:8321112
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    30. XM_036163472.1XP_036019365.1  adhesion G protein-coupled receptor L2 isoform X35

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641061
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    31. XM_036163469.1XP_036019362.1  adhesion G protein-coupled receptor L2 isoform X32

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9641072
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709965
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    32. XM_036163474.1XP_036019367.1  adhesion G protein-coupled receptor L2 isoform X37

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9791076
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709980
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    33. XM_036163473.1XP_036019366.1  adhesion G protein-coupled receptor L2 isoform X36

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881085
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    34. XM_036163468.1XP_036019361.1  adhesion G protein-coupled receptor L2 isoform X31

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881085
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    35. XM_036163476.1XP_036019369.1  adhesion G protein-coupled receptor L2 isoform X39

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881056
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    36. XM_036163467.1XP_036019360.1  adhesion G protein-coupled receptor L2 isoform X30

      UniProtKB/TrEMBL
      A0A0G2JH16
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9881096
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709989
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    37. XM_036163453.1XP_036019346.1  adhesion G protein-coupled receptor L2 isoform X17

      UniProtKB/TrEMBL
      A0A0G2JDK6
      Conserved Domains (7) summary
      smart00303
      Location:648700
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00008
      Location:342406
      HormR; Domain present in hormone receptors
      pfam02354
      Location:9791344
      Latrophilin; Latrophilin Cytoplasmic C-terminal region
      pfam16489
      Location:415624
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:710735
      7tm_GPCRs; TM helix 1 [structural motif]
      cl02549
      Location:15271
      OLF; Olfactomedin-like domain
      cl28897
      Location:709980
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153517.1: Suppressed sequence

      Description
      NM_153517.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.