cotl1 coactosin-like F-actin binding protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cotl1provided by ZNC
Official Full Name: coactosin-like F-actin binding protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8325
See related: Ensembl:ENSDARG00000026829 AllianceGenome:ZFIN:ZDB-GENE-030131-8325
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63983; wu:fb08h08
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be active in cortical actin cytoskeleton and site of polarized growth. Predicted to colocalize with actin filament. Is expressed in blood; epidermis; and periderm. Orthologous to human COTL1 (coactosin like F-actin binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (13203966..13216670)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (13235454..13248158)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb08h08.x1 (e-PCR)
- UniSTS:202768

fb07f11.x1 (e-PCR)
- UniSTS:202739

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
colocalizes_with actin filament	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cortical actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
is_active_in site of polarized growth	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: coactosin-like protein

Names: coactosin-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.