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    Eml5 echinoderm microtubule associated protein like 5 [ Mus musculus (house mouse) ]

    Gene ID: 319670, updated on 2-Nov-2024

    Summary

    Official Symbol
    Eml5provided by MGI
    Official Full Name
    echinoderm microtubule associated protein like 5provided by MGI
    Primary source
    MGI:MGI:2442513
    See related
    Ensembl:ENSMUSG00000051166 AllianceGenome:MGI:2442513
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C130068M19Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm and microtubule. Orthologous to human EML5 (EMAP like 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in frontal lobe adult (RPKM 12.3), cerebellum adult (RPKM 9.9) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Eml5 in Genome Data Viewer
    Location:
    12 E; 12 49.88 cM
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (98752863..98867770, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (98786604..98901511, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 7 Neighboring gene STARR-seq mESC enhancer starr_33000 Neighboring gene protein tyrosine phosphatase, non-receptor type 21 Neighboring gene STARR-positive B cell enhancer ABC_E9861 Neighboring gene zinc finger CCCH type containing 14 Neighboring gene predicted gene, 35463 Neighboring gene STARR-seq mESC enhancer starr_33001 Neighboring gene STARR-seq mESC enhancer starr_33002 Neighboring gene STARR-positive B cell enhancer ABC_E5348 Neighboring gene tetratricopeptide repeat domain 8 Neighboring gene STARR-seq mESC enhancer starr_33003 Neighboring gene predicted gene, 40554 Neighboring gene ribosomal protein L30, pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    echinoderm microtubule-associated protein-like 5
    Names
    EMAP-5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081191.1NP_001074660.1  echinoderm microtubule-associated protein-like 5

      See identical proteins and their annotated locations for NP_001074660.1

      Status: PROVISIONAL

      Source sequence(s)
      AC159193
      Consensus CDS
      CCDS36519.1
      UniProtKB/Swiss-Prot
      Q8BQM8, Q8BRL0, Q8R2W0
      UniProtKB/TrEMBL
      B2RY88
      Related
      ENSMUSP00000152709.2, ENSMUST00000223282.2
      Conserved Domains (4) summary
      COG2319
      Location:353845
      WD40; WD40 repeat [General function prediction only]
      pfam03451
      Location:547
      HELP; HELP motif
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      98752863..98867770 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515972.4XP_006516035.1  echinoderm microtubule-associated protein-like 5 isoform X3

      UniProtKB/TrEMBL
      B2RY88
      Conserved Domains (4) summary
      COG2319
      Location:13871806
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_006515970.4XP_006516033.1  echinoderm microtubule-associated protein-like 5 isoform X1

      UniProtKB/TrEMBL
      B2RY88
      Conserved Domains (4) summary
      COG2319
      Location:13921811
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_036157493.1XP_036013386.1  echinoderm microtubule-associated protein-like 5 isoform X4

      UniProtKB/TrEMBL
      B2RY88
      Conserved Domains (4) summary
      COG2319
      Location:14611867
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_017315105.2XP_017170594.1  echinoderm microtubule-associated protein-like 5 isoform X2

      UniProtKB/TrEMBL
      B2RY88
      Conserved Domains (4) summary
      COG2319
      Location:13951806
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    5. XM_030246770.1XP_030102630.1  echinoderm microtubule-associated protein-like 5 isoform X5

      UniProtKB/TrEMBL
      B2RY88
      Conserved Domains (4) summary
      COG2319
      Location:11531572
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:4580
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:431472
      HELP; HELP motif
      cl29593
      Location:483821
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    6. XM_006515976.2XP_006516039.1  echinoderm microtubule-associated protein-like 5 isoform X8

      Conserved Domains (4) summary
      COG2319
      Location:572991
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:882920
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:516586
      HELP; HELP motif
      cl29593
      Location:72317
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. XM_017315107.2XP_017170596.1  echinoderm microtubule-associated protein-like 5 isoform X6

      Conserved Domains (3) summary
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    8. XM_030246771.1XP_030102631.1  echinoderm microtubule-associated protein-like 5 isoform X7

      Conserved Domains (3) summary
      sd00039
      Location:64104
      7WD40; WD40 repeat [structural motif]
      pfam03451
      Location:547
      HELP; HELP motif
      cl29593
      Location:7251063
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. XR_004937514.1 RNA Sequence

    2. XR_004937513.1 RNA Sequence

    3. XR_001780456.2 RNA Sequence

    4. XR_004937508.1 RNA Sequence

    5. XR_001780453.2 RNA Sequence

    6. XR_003950056.1 RNA Sequence

    7. XR_004937516.1 RNA Sequence

    8. XR_004937510.1 RNA Sequence

    9. XR_004937509.1 RNA Sequence

    10. XR_003950058.1 RNA Sequence

    11. XR_004937512.1 RNA Sequence

    12. XR_004937511.1 RNA Sequence

    13. XR_001780457.2 RNA Sequence

    14. XR_001780455.2 RNA Sequence

    15. XR_003950059.2 RNA Sequence

    16. XR_004937515.1 RNA Sequence