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    Ccdc58 Coiled-coil domain-containing 58 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40159, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ccdc58provided by FlyBase
    Official Full Name
    Coiled-coil domain-containing 58provided by FlyBase
    Primary source
    FLYBASE:FBgn0036909
    Locus tag
    Dmel_CG15881
    See related
    AllianceGenome:FB:FBgn0036909
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:HL01254; CG15881; Dmel\CG15881
    Summary
    Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Is expressed in several structures, including adult heart; anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and posterior endoderm. Orthologous to human MIX23 (mitochondrial matrix import factor 23). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See Ccdc58 in Genome Data Viewer
    Location:
    76C6-76C6; 3-46 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19805181..19806932)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19798281..19800032)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 76a Neighboring gene Torsin interacting protein Neighboring gene uncharacterized protein Neighboring gene karyopherin alpha1 Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 305a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis. Ratan R, et al. Genetics, 2008 Feb. PMID 18245351, Free PMC Article
    2. Identification of critical host mitochondrion-associated genes during Ehrlichia chaffeensis infections. Von Ohlen T, et al. Infect Immun, 2012 Oct. PMID 22851751, Free PMC Article
    3. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article
    4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    5. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Coiled-coil domain-containing 58
    Names
    CG15881-PA
    CG15881-PB
    CG15881-PC
    Ccdc58-PA
    Ccdc58-PB
    Ccdc58-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19805181..19806932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140893.3 → NP_649150.1  Coiled-coil domain-containing 58, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649150.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUT5
      Related
      FBpp0074648
      Conserved Domains (1) summary
      pfam09774
      Location:4 → 111
      Cid2; Caffeine-induced death protein 2

    2. NM_001300192.1 → NP_001287121.1  Coiled-coil domain-containing 58, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287121.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUT5
      Conserved Domains (1) summary
      pfam09774
      Location:4 → 111
      Cid2; Caffeine-induced death protein 2

    3. NM_168819.3 → NP_730454.2  Coiled-coil domain-containing 58, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730454.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW41
      Related
      FBpp0074649
      Conserved Domains (1) summary
      pfam09774
      Location:5 → 128
      Cid2; Caffeine-induced death protein 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KUT5 Q7KUT5
    Q9VW41 Q9VW41

    Gene LinkOut

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