Rpp14 ribonuclease P 14 subunit [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rpp14provided by MGI
Official Full Name: ribonuclease P 14 subunitprovided by MGI
Primary source: MGI:MGI:1914303
See related: Ensembl:ENSMUSG00000023156 AllianceGenome:MGI:1914303
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610511E03Rik
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of multimeric ribonuclease P complex. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RPP14 (ribonuclease P/MRP subunit p14). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in bladder adult (RPKM 6.3), placenta adult (RPKM 6.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 14 A1; 14 4.7 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	14	NC_000080.7 (14377927..14389460, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	14	NC_000080.6 (8080313..8091846)

Chromosome 14 - NC_000080.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

Rpp14 (e-PCR), detects polymorphism
- UniSTS:507197

AA682089 (e-PCR)
- UniSTS:160354

RH124359 (e-PCR)
- UniSTS:161181

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ribonuclease P RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
enables ribonuclease P RNA binding	ISS Inferred from Sequence or Structural Similarity more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in tRNA 5'-leader removal	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info
involved_in tRNA 5'-leader removal	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of multimeric ribonuclease P complex	IBA Inferred from Biological aspect of Ancestor more info
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of multimeric ribonuclease P complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ribonuclease P protein subunit p14

Names: ribonuclease P 14kDa subunit

NP_080214.1

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.