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    fnta.S farnesyltransferase, CAAX box, subunit alpha S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100137632, updated on 4-Nov-2024

    Summary

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    Official Symbol
    fnta.S
    Official Full Name
    farnesyltransferase, CAAX box, subunit alpha S homeolog
    Primary source
    Xenbase:XB-GENE-865915
    Locus tag
    XELAEV_18009694mg
    See related
    EnsemblRapid:ENSXLAG00005028849 AllianceGenome:Xenbase:XB-GENE-865915
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    fnta; fpta; ptar2; pggt1a; FTase-alpha
    Summary
    Predicted to enable CAAX-protein geranylgeranyltransferase activity and protein farnesyltransferase activity. Predicted to act upstream of or within protein farnesylation and protein geranylgeranylation. Predicted to be located in cytoplasm. Predicted to be part of CAAX-protein geranylgeranyltransferase complex and protein farnesyltransferase complex. Orthologous to human FNTA (farnesyltransferase, CAAX box, subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See fnta.S in Genome Data Viewer
    Location:
    chromosome: 1S
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (86223784..86237108)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (81069730..81083082)

    Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 3 S homeolog Neighboring gene uncharacterized LOC121399359 Neighboring gene thymosin beta-10 Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 1 S homeolog Neighboring gene SH2 domain containing 4A S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables CAAX-protein geranylgeranyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables prenyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein prenyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein farnesylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein geranylgeranylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein prenylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of CAAX-protein geranylgeranyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein farnesyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    farnesyltransferase, CAAX box, subunit alpha S homeolog
    Names
    farnesyltransferase, CAAX box, alpha S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114783.1 → NP_001108255.1  farnesyltransferase, CAAX box, subunit alpha S homeolog

      See identical proteins and their annotated locations for NP_001108255.1

      Status: PROVISIONAL

      Source sequence(s)
      BC157425
      UniProtKB/TrEMBL
      A0A974DU28, A9ULW7
      Related
      ENSXLAP00005086123.1, ENSXLAT00005087785.1
      Conserved Domains (2) summary
      PLN02789
      Location:59 → 351
      PLN02789; farnesyltranstransferase
      pfam01239
      Location:178 → 204
      PPTA; Protein prenyltransferase alpha subunit repeat

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      86223784..86237108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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