rbm14b RNA binding motif protein 14b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rbm14bprovided by ZNC
Official Full Name: RNA binding motif protein 14bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2455
See related: Ensembl:ENSDARG00000103834 AllianceGenome:ZFIN:ZDB-GENE-040426-2455
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rbm14; zgc:85696
Summary: Predicted to enable RNA binding activity and zinc ion binding activity. Acts upstream of with a negative effect on BMP signaling pathway. Predicted to be active in nucleolus. Orthologous to several human genes including RBM14 (RNA binding motif protein 14). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (7019911..7036570)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (6786469..6804533)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development.
Title: Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_negative_effect BMP signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within dorsal/ventral pattern formation	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: RNA-binding protein 14b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212808.1 → NP_997973.1 RNA-binding protein 14b

See identical proteins and their annotated locations for NP_997973.1

Status: PROVISIONAL

Source sequence(s)

BC068361

UniProtKB/TrEMBL

A0A8N7XJ42, F1QG19, Q6NV05, Q6PHC6

Related

ENSDARP00000133021.1, ENSDART00000172421.3

Conserved Domains (2) summary

cd12343
Location:84 → 149

RRM1_2_CoAA_like; RNA recognition motif 1 and 2 in RRM-containing coactivator activator/modulator (CoAA) and similar proteins

cd12608
Location:7 → 75

RRM1_CoAA; RNA recognition motif 1 in vertebrate RRM-containing coactivator activator/modulator (CoAA)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

7019911..7036570

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021477448.2 → XP_021333123.1 RNA-binding protein 14b isoform X1

UniProtKB/TrEMBL

A0A8M9Q1B8

Conserved Domains (3) summary

cd12343
Location:84 → 149

RRM1_2_CoAA_like; RNA recognition motif 1 and 2 in RRM-containing coactivator activator/modulator (CoAA) and similar proteins

cd12608
Location:7 → 75

RRM1_CoAA; RNA recognition motif 1 in vertebrate RRM-containing coactivator activator/modulator (CoAA)

cl26705
Location:150 → 187

AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]