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    hoxd11a homeobox D11a [ Danio rerio (zebrafish) ]

    Gene ID: 30405, updated on 2-Nov-2024

    Summary

    Official Symbol
    hoxd11aprovided by ZNC
    Official Full Name
    homeobox D11aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-117
    See related
    Ensembl:ENSDARG00000059267 AllianceGenome:ZFIN:ZDB-GENE-990415-117
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hoxc11; hoxd11; fk50b10; hoxd-11; sb:eu641; wu:fk50b10
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic skeletal joint morphogenesis and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including fin; mesenchyme; pectoral fin bud; pectoral fin field; and tail bud. Orthologous to human HOXD11 (homeobox D11). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See hoxd11a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (1975818..1978090, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (1975021..1977293, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene homeobox D9a Neighboring gene homeobox D10a Neighboring gene homeobox D12a Neighboring gene homeobox D13a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in embryonic skeletal joint morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    homeobox protein Hox-D11a
    Names
    homeo box D11a
    homeobox gene D-11
    homeobox protein Hox-C11
    hox-C11
    hox-D11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131167.1NP_571242.1  homeobox protein Hox-D11a

      See identical proteins and their annotated locations for NP_571242.1

      Status: PROVISIONAL

      Source sequence(s)
      BX322661
      UniProtKB/Swiss-Prot
      O57372, Q29RC6, Q4JMC9, Q90470
      Related
      ENSDARP00000076780.4, ENSDART00000082344.5
      Conserved Domains (2) summary
      pfam00046
      Location:207260
      Homeobox; Homeobox domain
      pfam12045
      Location:23158
      DUF3528; Protein of unknown function (DUF3528)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      1975818..1978090 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)