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    Abcf2 ATP-binding cassette, sub-family F member 2 [ Mus musculus (house mouse) ]

    Gene ID: 27407, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Abcf2provided by MGI
    Official Full Name
    ATP-binding cassette, sub-family F member 2provided by MGI
    Primary source
    MGI:MGI:1351657
    See related
    Ensembl:ENSMUSG00000028953 AllianceGenome:MGI:1351657
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drr3; E430001O06; 0710005O05Rik
    Summary
    Predicted to enable ATP binding activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to several human genes including ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 70.0), thymus adult (RPKM 32.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Abcf2 in Genome Data Viewer
    Location:
    5 A3; 5 11.93 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24770339..24782465, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24565341..24577467, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box-containing 10 Neighboring gene IQ motif containing with AAA domain 1 like Neighboring gene STARR-positive B cell enhancer ABC_E6314 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g pseudogene Neighboring gene chondroitin polymerizing factor 2 Neighboring gene microRNA 671

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A novel family of repeat sequences in the mouse genome responsive to retinoic acid. Sam M, et al. Mamm Genome, 1996 Oct. PMID 8854861
    2. CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending. Krähling AM, et al. PLoS Genet, 2013. PMID 24339785, Free PMC Article
    3. Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity. Mattebo A, et al. Sci Rep, 2021 Aug 5. PMID 34354145, Free PMC Article
    4. Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. Schriml LM, et al. Genomics, 2000 Feb 15. PMID 10708515
    5. Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pan J, et al. Am J Reprod Immunol, 2015 Sep. PMID 26073538

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family F member 2
    Names
    ATP-binding cassette, sub-family F (GCN20), member 2
    developmentally regulated repeat element-containing transcript 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190443.2 → NP_001177372.1  ATP-binding cassette sub-family F member 2 isoform 2

      See identical proteins and their annotated locations for NP_001177372.1

      Status: VALIDATED

      Source sequence(s)
      AC116136
      UniProtKB/TrEMBL
      Q3UVI9
      Conserved Domains (3) summary
      cd03221
      Location:90 → 306
      ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
      COG0488
      Location:87 → 607
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      pfam12848
      Location:300 → 370
      ABC_tran_Xtn; ABC transporter

    2. NM_001359205.2 → NP_001346134.1  ATP-binding cassette sub-family F member 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC116136
      Consensus CDS
      CCDS19125.1
      UniProtKB/Swiss-Prot
      Q3UA24, Q8C1S5, Q99LE6, Q9JL48
      UniProtKB/TrEMBL
      Q3UVI9
      Conserved Domains (1) summary
      COG0488
      Location:88 → 608
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

    3. NM_001429004.1 → NP_001415933.1  ATP-binding cassette sub-family F member 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC116136
      UniProtKB/Swiss-Prot
      Q3UA24, Q8C1S5, Q99LE6, Q9JL48

    4. NM_001429005.1 → NP_001415934.1  ATP-binding cassette sub-family F member 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC116136
      UniProtKB/Swiss-Prot
      Q3UA24, Q8C1S5, Q99LE6, Q9JL48

    5. NM_001429006.1 → NP_001415935.1  ATP-binding cassette sub-family F member 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116136

    6. NM_001429007.1 → NP_001415936.1  ATP-binding cassette sub-family F member 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116136

    7. NM_001429008.1 → NP_001415937.1  ATP-binding cassette sub-family F member 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116136

    8. NM_001429009.1 → NP_001415938.1  ATP-binding cassette sub-family F member 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116136

    9. NM_001429010.1 → NP_001415939.1  ATP-binding cassette sub-family F member 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC116136

    10. NM_001429011.1 → NP_001415940.1  ATP-binding cassette sub-family F member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC116136

    11. NM_001429012.1 → NP_001415941.1  ATP-binding cassette sub-family F member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC116136

    12. NM_001429013.1 → NP_001415942.1  ATP-binding cassette sub-family F member 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC116136

    13. NM_013853.3 → NP_038881.1  ATP-binding cassette sub-family F member 2 isoform 1

      See identical proteins and their annotated locations for NP_038881.1

      Status: VALIDATED

      Source sequence(s)
      AC116136
      Consensus CDS
      CCDS19125.1
      UniProtKB/Swiss-Prot
      Q3UA24, Q8C1S5, Q99LE6, Q9JL48
      UniProtKB/TrEMBL
      Q3UVI9
      Related
      ENSMUSP00000030795.9, ENSMUST00000030795.10
      Conserved Domains (1) summary
      COG0488
      Location:88 → 608
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      24770339..24782465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535727.4 → XP_006535790.1  ATP-binding cassette sub-family F member 2 isoform X1

      Conserved Domains (1) summary
      COG0488
      Location:88 → 608
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99LE6.1 GenPept UniProtKB/Swiss-Prot:Q99LE6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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