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    si:ch211-117n7.6 si:ch211-117n7.6 [ Danio rerio (zebrafish) ]

    Gene ID: 555902, updated on 2-Nov-2024

    Summary

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    Official Symbol
    si:ch211-117n7.6provided by ZNC
    Official Full Name
    si:ch211-117n7.6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-474
    See related
    Ensembl:ENSDARG00000092071 AllianceGenome:ZFIN:ZDB-GENE-060503-474
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable lysophospholipase activity and monoacylglycerol lipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ABHD12B (abhydrolase domain containing 12B). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See si:ch211-117n7.6 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (9889714..9895616, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (9557004..9563711, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene si:ch211-117n7.7 Neighboring gene transmembrane 9 superfamily member 3 Neighboring gene S1 RNA binding domain 1 Neighboring gene uncharacterized LOC110440194

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lysophospholipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoacylglycerol catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylserine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    lysophosphatidylserine lipase ABHD12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      9889714..9895616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_678562.8 → XP_683654.2  lysophosphatidylserine lipase ABHD12

      UniProtKB/TrEMBL
      A0A8N7TD50, A8E7H0
      Related
      ENSDARP00000122889.1, ENSDART00000142629.2
      Conserved Domains (2) summary
      cl26327
      Location:138 → 316
      Abhydrolase_1; alpha/beta hydrolase fold
      cl27026
      Location:77 → 171
      AXE1; Acetyl xylan esterase (AXE1)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394867.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      227124..233709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472679.2 → XP_021328354.1  lysophosphatidylserine lipase ABHD12

      UniProtKB/TrEMBL
      A0A8N7TD50, A8E7H0
      Conserved Domains (2) summary
      cl26327
      Location:138 → 316
      Abhydrolase_1; alpha/beta hydrolase fold
      cl27026
      Location:77 → 171
      AXE1; Acetyl xylan esterase (AXE1)
    Nucleotide Protein
    Heading Accession and Version

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