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    atrn attractin [ Danio rerio (zebrafish) ]

    Gene ID: 794975, updated on 14-Nov-2024

    Summary

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    Official Symbol
    atrnprovided by ZNC
    Official Full Name
    attractinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090312-21
    See related
    Ensembl:ENSDARG00000062164 AllianceGenome:ZFIN:ZDB-GENE-090312-21
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-259n11.1
    Summary
    Predicted to enable chromatin binding activity. Acts upstream of or within regulation of actomyosin structure organization. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in blastomere; forebrain; midbrain; and otic vesicle. Orthologous to human ATRN (attractin). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See atrn in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (14006133..14181765)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (13875331..14048438)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 3 Neighboring gene ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase) Neighboring gene uncharacterized LOC101884819 Neighboring gene GDNF family receptor alpha 4a Neighboring gene uncharacterized LOC137487375

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Attractin Participates in Schizophrenia by Affecting Testosterone Levels. Li N, et al. Front Cell Dev Biol, 2021. PMID 34869343, Free PMC Article
    2. Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly. Sun Q, et al. Int J Biol Sci, 2017. PMID 28924386, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of actomyosin structure organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of actomyosin structure organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    attractin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001353962.1 → NP_001340891.1  attractin

      Status: VALIDATED

      Source sequence(s)
      CR388098, CR589874, CT583702
      UniProtKB/TrEMBL
      A0A8N1Z1N4, B8JI13
      Related
      ENSDARP00000083961.7, ENSDART00000089528.7
      Conserved Domains (8) summary
      cd03597
      Location:740 → 869
      CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
      cd00041
      Location:83 → 197
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00055
      Location:1016 → 1061
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      sd00038
      Location:506 → 563
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:506 → 558
      Kelch_1; Kelch motif
      pfam01437
      Location:881 → 932
      PSI; Plexin repeat
      pfam13418
      Location:453 → 496
      Kelch_4; Galactose oxidase, central domain
      cl28614
      Location:291 → 440
      BTB; Broad-Complex, Tramtrack and Bric a brac

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      14006133..14181765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394873.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      236087..418369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001145615.1: Suppressed sequence

      Description
      NM_001145615.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version

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