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    eif4e2rs1 eukaryotic translation initiation factor 4E family member 2 related sequence 1 [ Danio rerio (zebrafish) ]

    Gene ID: 393732, updated on 2-Nov-2024

    Summary

    Official Symbol
    eif4e2rs1provided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 4E family member 2 related sequence 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1728
    See related
    Ensembl:ENSDARG00000015835 AllianceGenome:ZFIN:ZDB-GENE-040426-1728
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    eIF4E2B; zgc:73242
    Summary
    Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See eif4e2rs1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (44427932..44440737)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (44622528..44635333)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene discs, large homolog 4b (Drosophila) Neighboring gene eph receptor B4b Neighboring gene si:ch1073-228j22.2 Neighboring gene centrobin, centrosomal BRCA2 interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC73242

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA 7-methylguanosine cap binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic translation initiation factor 4F complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 4E family member 2 related sequence 1
    Names
    eif4E-2B
    eukaryotic translation initiation factor 4E class II 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200759.2NP_957053.1  eukaryotic translation initiation factor 4E family member 2 related sequence 1

      See identical proteins and their annotated locations for NP_957053.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01118710, EH485715, FO904893
      UniProtKB/TrEMBL
      Q6PBU4, U3RD49
      Related
      ENSDARP00000132205.1, ENSDART00000160207.3
      Conserved Domains (1) summary
      pfam01652
      Location:52208
      IF4E; Eukaryotic initiation factor 4E

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      44427932..44440737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353532.3XP_017209021.1  eukaryotic translation initiation factor 4E family member 2 related sequence 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M6YXN8