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    os9 OS9 endoplasmic reticulum lectin [ Danio rerio (zebrafish) ]

    Gene ID: 553455, updated on 12-Sep-2024

    Summary

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    Official Symbol
    os9provided by ZNC
    Official Full Name
    OS9 endoplasmic reticulum lectinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-32
    See related
    Ensembl:ENSDARG00000020301 AllianceGenome:ZFIN:ZDB-GENE-060929-32
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153838
    Summary
    Predicted to be involved in retrograde protein transport, ER to cytosol and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human OS9 (OS9 endoplasmic reticulum lectin). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See os9 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (39202685..39218590, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (39203994..39221048, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene tachykinin precursor 3b Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, like b Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 1b Neighboring gene Rho guanine nucleotide exchange factor (GEF) 25b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum. Wang Y, et al. J Biol Chem, 2007 Dec 14. PMID 17932042
    2. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153838

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde protein transport, ER to cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein OS-9
    Names
    amplified in osteosarcoma
    osteosarcoma amplified 9, endoplasmic reticulum lectin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075108.1 → NP_001068576.1  protein OS-9

      See identical proteins and their annotated locations for NP_001068576.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124472
      UniProtKB/TrEMBL
      Q08C06
      Related
      ENSDARP00000120218.1, ENSDART00000133305.3
      Conserved Domains (2) summary
      pfam07915
      Location:72 → 143
      PRKCSH; Glucosidase II beta subunit-like protein
      cl06793
      Location:137 → 195
      PRKCSH; Glucosidase II beta subunit-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      39202685..39218590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166042.5 → XP_005166099.1  protein OS-9 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BDH0
      Related
      ENSDART00000041882.9
      Conserved Domains (2) summary
      pfam07915
      Location:106 → 177
      PRKCSH; Glucosidase II beta subunit-like protein
      cl06793
      Location:171 → 229
      PRKCSH; Glucosidase II beta subunit-like protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394661.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      76463..92343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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