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    sipa1l1.L signal induced proliferation associated 1 like 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 446241, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sipa1l1.L
    Official Full Name
    signal induced proliferation associated 1 like 1 L homeolog
    Primary source
    Xenbase:XB-GENE-866800
    Locus tag
    XELAEV_18039895mg
    See related
    EnsemblRapid:ENSXLAG00005031679
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    spar1; sipa1l1
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    Genomic context

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    See sipa1l1.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (98649676..98805378, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (83977396..84133613, complement)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene D4, zinc and double PHD fingers, family 3 L homeolog Neighboring gene uncharacterized LOC121397140 Neighboring gene regulator of G-protein signaling 6 L homeolog Neighboring gene pecanex 1 L homeolog Neighboring gene mitogen-activated protein kinase kinase kinase 9 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    signal-induced proliferation-associated 1-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      98649676..98805378 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018231085.2 → XP_018086574.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J0TKV5, Q6AZH2
      Conserved Domains (4) summary
      cd00992
      Location:952 → 1022
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:627 → 806
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1488 → 1737
      SPAR_C; C-terminal domain of SPAR protein
      NF033845
      Location:1213 → 1437
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

    2. XM_018231087.2 → XP_018086576.1  signal-induced proliferation-associated 1-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8J0TD35, Q6AZH2
      Related
      ENSXLAP00005095106.1, ENSXLAT00005096837.1

    3. XM_018231086.2 → XP_018086575.1  signal-induced proliferation-associated 1-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1L8FAI0, A0A974C8M5, Q6AZH2

    4. XM_018231081.2 → XP_018086570.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J0TKV5, Q6AZH2
      Conserved Domains (4) summary
      cd00992
      Location:952 → 1022
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:627 → 806
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1488 → 1737
      SPAR_C; C-terminal domain of SPAR protein
      NF033845
      Location:1213 → 1437
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

    5. XM_041573296.1 → XP_041429230.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J0TKV5, Q6AZH2
      Related
      ENSXLAP00005094999.1, ENSXLAT00005096714.1
      Conserved Domains (4) summary
      cd00992
      Location:952 → 1022
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:627 → 806
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1488 → 1737
      SPAR_C; C-terminal domain of SPAR protein
      NF033845
      Location:1213 → 1437
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

    6. XM_018231082.2 → XP_018086571.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J0TKV5, Q6AZH2
      Conserved Domains (4) summary
      cd00992
      Location:952 → 1022
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:627 → 806
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:1488 → 1737
      SPAR_C; C-terminal domain of SPAR protein
      NF033845
      Location:1213 → 1437
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    Nucleotide Protein Strain
    Heading Accession and Version

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