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    Mybpc1 myosin binding protein C, slow-type [ Mus musculus (house mouse) ]

    Gene ID: 109272, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Mybpc1provided by MGI
    Official Full Name
    myosin binding protein C, slow-typeprovided by MGI
    Primary source
    MGI:MGI:1336213
    See related
    Ensembl:ENSMUSG00000020061 AllianceGenome:MGI:1336213
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    8030451F13Rik
    Summary
    Predicted to enable myosin binding activity. Predicted to be involved in sarcomere organization. Predicted to act upstream of or within muscle contraction. Predicted to be located in cytoskeleton. Predicted to be active in M band. Is expressed in several structures, including brain; hindlimb; reproductive system; skeletal musculature; and urinary system. Used to study congenital myopathy. Human ortholog(s) of this gene implicated in congenital myopathy 16; distal arthrogryposis type 1B; and lethal congenital contracture syndrome 4. Orthologous to human MYBPC1 (myosin binding protein C1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in limb E14.5 (RPKM 9.6), mammary gland adult (RPKM 6.9) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mybpc1 in Genome Data Viewer
    Location:
    10 C1; 10 43.99 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (88354141..88441051, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (88518279..88605229, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11453 Neighboring gene N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits Neighboring gene STARR-positive B cell enhancer ABC_E5162 Neighboring gene STARR-positive B cell enhancer mm9_chr10:87872706-87873007 Neighboring gene STARR-positive B cell enhancer ABC_E2333 Neighboring gene STARR-positive B cell enhancer ABC_E3906 Neighboring gene synaptonemal complex protein 3 Neighboring gene choline phosphotransferase 1 Neighboring gene STARR-seq mESC enhancer starr_27496 Neighboring gene STARR-seq mESC enhancer starr_27498 Neighboring gene STARR-positive B cell enhancer ABC_E6897 Neighboring gene STARR-seq mESC enhancer starr_27500 Neighboring gene STARR-seq mESC enhancer starr_27501 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene predicted gene, 48106

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor. Geist Hauserman J, et al. JCI Insight, 2021 Oct 8. PMID 34437302, Free PMC Article
    2. Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow. Ackermann MA, et al. FASEB J, 2013 Aug. PMID 23657818, Free PMC Article
    3. Fast and slow skeletal myosin binding protein-C and aging. Perazza LR, et al. Geroscience, 2023 Apr. PMID 36409445, Free PMC Article
    4. Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle. Gautel M, et al. Circ Res, 1998 Jan 9-23. PMID 9440711
    5. Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles. Kurasawa M, et al. Muscle Nerve, 1999 Feb. PMID 10024132

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Fast and slow skeletal myosin binding protein-C and aging.
      Title: Fast and slow skeletal myosin binding protein-C and aging.
    2. Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor.
      Title: Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor.
    3. Data show that the NH2 and COOH termini of myosin binding protein C slow type (sMyBP-C) have distinct functions, which are regulated by differential splicing, and are compromized by the presence of missense point mutations linked to muscle disease.
      Title: Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables myosin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural constituent of cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within muscle contraction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in sarcomere organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in M band IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-binding protein C, slow-type
    Names
    MyBP-C slow
    Slow-type C-protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252372.1 → NP_001239301.1  myosin-binding protein C, slow-type isoform 1

      See identical proteins and their annotated locations for NP_001239301.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
      Source sequence(s)
      AK132188, BB669565, BC062158, BY135230
      Consensus CDS
      CCDS56739.1
      UniProtKB/TrEMBL
      A0A571BEN1, D3YU50
      Related
      ENSMUSP00000112699.2, ENSMUST00000119185.8
      Conserved Domains (8) summary
      cd00096
      Location:1033 → 1098
      Ig; Immunoglobulin domain
      cd05894
      Location:518 → 603
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:521 → 603
      IG_like; Immunoglobulin like
      cd00063
      Location:607 → 696
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1016 → 1105
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:51 → 135
      ig; Immunoglobulin domain
      pfam03755
      Location:136 → 235
      YicC_N; YicC-like family, N-terminal region
      cl11960
      Location:826 → 883
      Ig; Immunoglobulin domain

    2. NM_175418.5 → NP_780627.2  myosin-binding protein C, slow-type isoform 2

      See identical proteins and their annotated locations for NP_780627.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      BB669565, BC062158, BY135230
      Consensus CDS
      CCDS48666.1
      UniProtKB/TrEMBL
      A0A571BEN1, Q6P6L5
      Related
      ENSMUSP00000112615.2, ENSMUST00000121629.8
      Conserved Domains (8) summary
      cd00096
      Location:1047 → 1112
      Ig; Immunoglobulin domain
      cd05894
      Location:532 → 617
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:535 → 617
      IG_like; Immunoglobulin like
      cd00063
      Location:621 → 710
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1030 → 1119
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:65 → 149
      ig; Immunoglobulin domain
      pfam03755
      Location:150 → 249
      YicC_N; YicC-like family, N-terminal region
      cl11960
      Location:840 → 897
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      88354141..88441051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513045.5 → XP_006513108.1  myosin-binding protein C, slow-type isoform X1

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:90 → 185
      IG_like; Immunoglobulin like
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1073 → 1162
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cl11960
      Location:882 → 940
      Ig; Immunoglobulin domain

    2. XM_006513047.5 → XP_006513110.1  myosin-binding protein C, slow-type isoform X2

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:90 → 185
      IG_like; Immunoglobulin like
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1073 → 1162
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cl11960
      Location:882 → 940
      Ig; Immunoglobulin domain

    3. XM_006513053.5 → XP_006513116.1  myosin-binding protein C, slow-type isoform X8

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:531 → 616
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:64 → 159
      IG_like; Immunoglobulin like
      cd00063
      Location:620 → 709
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1047 → 1136
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:209 → 242
      THB; Tri-helix bundle domain
      cl11960
      Location:856 → 914
      Ig; Immunoglobulin domain

    4. XM_006513049.5 → XP_006513112.1  myosin-binding protein C, slow-type isoform X4

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:543 → 628
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:76 → 171
      IG_like; Immunoglobulin like
      cd00063
      Location:632 → 721
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1059 → 1148
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:221 → 254
      THB; Tri-helix bundle domain
      cl11960
      Location:868 → 926
      Ig; Immunoglobulin domain

    5. XM_006513052.5 → XP_006513115.1  myosin-binding protein C, slow-type isoform X7

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:532 → 617
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:65 → 160
      IG_like; Immunoglobulin like
      cd00063
      Location:621 → 710
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1048 → 1137
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:210 → 243
      THB; Tri-helix bundle domain
      cl11960
      Location:857 → 915
      Ig; Immunoglobulin domain

    6. XM_036155497.1 → XP_036011390.1  myosin-binding protein C, slow-type isoform X12

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd00063
      Location:621 → 710
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1048 → 1137
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:210 → 243
      THB; Tri-helix bundle domain
      cd00096
      Location:61 → 64
      Ig; Ig strand A [structural motif]
      cd05894
      Location:532 → 617
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      cl11960
      Location:60 → 160
      Ig; Immunoglobulin domain

    7. XM_006513046.5 → XP_006513109.1  myosin-binding protein C, slow-type isoform X3

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:545 → 630
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:78 → 173
      IG_like; Immunoglobulin like
      cd00063
      Location:634 → 723
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1061 → 1150
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:223 → 256
      THB; Tri-helix bundle domain
      cl11960
      Location:870 → 928
      Ig; Immunoglobulin domain

    8. XM_006513054.5 → XP_006513117.1  myosin-binding protein C, slow-type isoform X9

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00409
      Location:90 → 185
      IG; Immunoglobulin
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1073 → 1162
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cl11960
      Location:882 → 940
      Ig; Immunoglobulin domain

    9. XM_006513057.5 → XP_006513120.1  myosin-binding protein C, slow-type isoform X13

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:518 → 603
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:51 → 146
      IG_like; Immunoglobulin like
      cd00063
      Location:607 → 696
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1034 → 1123
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:196 → 229
      THB; Tri-helix bundle domain
      cl11960
      Location:843 → 901
      Ig; Immunoglobulin domain

    10. XM_006513050.5 → XP_006513113.1  myosin-binding protein C, slow-type isoform X6

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:90 → 185
      IG_like; Immunoglobulin like
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1055 → 1144
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cl11960
      Location:864 → 922
      Ig; Immunoglobulin domain

    11. XM_036155496.1 → XP_036011389.1  myosin-binding protein C, slow-type isoform X10

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1055 → 1144
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cd00096
      Location:86 → 89
      Ig; Ig strand A [structural motif]
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      cl11960
      Location:85 → 185
      Ig; Immunoglobulin domain

    12. XM_030244822.2 → XP_030100682.1  myosin-binding protein C, slow-type isoform X16

      UniProtKB/TrEMBL
      A0A571BEN1
      Related
      ENSMUSP00000158844.2, ENSMUST00000238199.2
      Conserved Domains (6) summary
      cd05894
      Location:531 → 616
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:64 → 159
      IG_like; Immunoglobulin like
      cd00063
      Location:620 → 709
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1029 → 1118
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:209 → 242
      THB; Tri-helix bundle domain
      cl11960
      Location:838 → 896
      Ig; Immunoglobulin domain

    13. XM_006513058.5 → XP_006513121.1  myosin-binding protein C, slow-type isoform X15

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:532 → 617
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:65 → 160
      IG_like; Immunoglobulin like
      cd00063
      Location:621 → 710
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1030 → 1119
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:210 → 243
      THB; Tri-helix bundle domain
      cl11960
      Location:839 → 897
      Ig; Immunoglobulin domain

    14. XM_036155499.1 → XP_036011392.1  myosin-binding protein C, slow-type isoform X18

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd00063
      Location:621 → 710
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1030 → 1119
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:210 → 243
      THB; Tri-helix bundle domain
      cd00096
      Location:61 → 64
      Ig; Ig strand A [structural motif]
      cd05894
      Location:532 → 617
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      cl11960
      Location:60 → 160
      Ig; Immunoglobulin domain

    15. XM_006513055.5 → XP_006513118.1  myosin-binding protein C, slow-type isoform X11

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:545 → 630
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:78 → 173
      IG_like; Immunoglobulin like
      cd00063
      Location:634 → 723
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1043 → 1132
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:223 → 256
      THB; Tri-helix bundle domain
      cl11960
      Location:852 → 910
      Ig; Immunoglobulin domain

    16. XM_036155498.1 → XP_036011391.1  myosin-binding protein C, slow-type isoform X17

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd00063
      Location:646 → 735
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1055 → 1144
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:235 → 268
      THB; Tri-helix bundle domain
      cd00096
      Location:86 → 89
      Ig; Ig strand A [structural motif]
      cd05894
      Location:557 → 642
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      cl11960
      Location:85 → 185
      Ig; Immunoglobulin domain

    17. XM_006513056.3 → XP_006513119.1  myosin-binding protein C, slow-type isoform X14

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:518 → 603
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:51 → 146
      IG_like; Immunoglobulin like
      cd00063
      Location:607 → 696
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1034 → 1123
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:196 → 229
      THB; Tri-helix bundle domain
      cl11960
      Location:843 → 901
      Ig; Immunoglobulin domain

    18. XM_006513048.3 → XP_006513111.1  myosin-binding protein C, slow-type isoform X5

      UniProtKB/TrEMBL
      A0A571BEN1
      Conserved Domains (6) summary
      cd05894
      Location:543 → 628
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00410
      Location:76 → 171
      IG_like; Immunoglobulin like
      cd00063
      Location:632 → 721
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1059 → 1148
      I-set; Immunoglobulin I-set domain
      pfam18362
      Location:221 → 254
      THB; Tri-helix bundle domain
      cl11960
      Location:868 → 926
      Ig; Immunoglobulin domain

    RNA

    1. XR_380342.5 RNA Sequence

    2. XR_004936034.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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