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    Celf2 CUGBP, Elav-like family member 2 [ Mus musculus (house mouse) ]

    Gene ID: 14007, updated on 2-Nov-2024

    Summary

    Official Symbol
    Celf2provided by MGI
    Official Full Name
    CUGBP, Elav-like family member 2provided by MGI
    Primary source
    MGI:MGI:1338822
    See related
    Ensembl:ENSMUSG00000002107 AllianceGenome:MGI:1338822
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Etr-3; Napor; CELF-2; Cugbp2; mETR-3; CUG-BP2; Napor-2; B230218O03; B230345P09Rik; D230046B21Rik
    Summary
    Enables lncRNA binding activity. Acts upstream of or within mRNA splice site recognition. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; foregut; hemolymphoid system gland; limb; and urinary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Orthologous to human CELF2 (CUGBP Elav-like family member 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 23.9), frontal lobe adult (RPKM 20.6) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Celf2 in Genome Data Viewer
    Location:
    2 A1; 2 3.69 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (6544505..7401345, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (6539694..7396341, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03593 Neighboring gene USP6 N-terminal like Neighboring gene predicted gene 13388 Neighboring gene predicted gene 13391 Neighboring gene predicted gene, 52546 Neighboring gene STARR-seq mESC enhancer starr_03597 Neighboring gene STARR-seq mESC enhancer starr_03598 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:6628430-6628675 Neighboring gene STARR-seq mESC enhancer starr_03599 Neighboring gene STARR-seq mESC enhancer starr_03600 Neighboring gene STARR-seq mESC enhancer starr_03601 Neighboring gene RIKEN cDNA 5031426D15 gene Neighboring gene STARR-seq mESC enhancer starr_03602 Neighboring gene STARR-seq mESC enhancer starr_03603 Neighboring gene STARR-seq mESC enhancer starr_03604 Neighboring gene predicted gene, 24340 Neighboring gene STARR-seq mESC enhancer starr_03606 Neighboring gene STARR-seq mESC enhancer starr_03607 Neighboring gene STARR-seq mESC enhancer starr_03608 Neighboring gene STARR-seq mESC enhancer starr_03609 Neighboring gene STARR-seq mESC enhancer starr_03610 Neighboring gene STARR-seq mESC enhancer starr_03611 Neighboring gene STARR-seq mESC enhancer starr_03612 Neighboring gene actin, cytoplasmic 3-like Neighboring gene predicted gene, 30904

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lncRNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables pre-mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA splice site recognition IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mRNA splice site recognition ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in post-transcriptional gene silencing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Flemming body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    CUGBP Elav-like family member 2
    Names
    CUG triplet repeat, RNA binding protein 2
    CUG-BP- and ETR-3-like factor 2
    RNA-binding protein BRUNOL-3
    bruno-like protein 3
    elav-type RNA-binding protein 3
    mNapor
    neuroblastoma apoptosis-related RNA-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110228.1NP_001103698.1  CUGBP Elav-like family member 2 isoform 1

      See identical proteins and their annotated locations for NP_001103698.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1). Both variants 1 and 8 encode the same isoform.
      Source sequence(s)
      AF090697, AL845515, BC033049, CF536042
      Consensus CDS
      CCDS50494.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Related
      ENSMUSP00000110584.4, ENSMUST00000114934.11
      Conserved Domains (3) summary
      cd12638
      Location:434525
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:57140
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:149229
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    2. NM_001110229.2NP_001103699.1  CUGBP Elav-like family member 2 isoform 2

      See identical proteins and their annotated locations for NP_001103699.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, has multiple differences in the presence and absence of exons at its 5' end, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AL772190, AL845492, AL845515
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:432523
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    3. NM_001110230.2NP_001103700.1  CUGBP Elav-like family member 2 isoform 3

      See identical proteins and their annotated locations for NP_001103700.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AL772190, AL845492, AL845515
      Consensus CDS
      CCDS59633.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Related
      ENSMUSP00000138764.2, ENSMUST00000182706.8
      Conserved Domains (3) summary
      cd12638
      Location:428519
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    4. NM_001110231.2NP_001103701.1  CUGBP Elav-like family member 2 isoform 4

      See identical proteins and their annotated locations for NP_001103701.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and 3' UTR, has multiple differences in the presence and absence of exons at its 5' end, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (4) that is shorter than isoform 1.
      Source sequence(s)
      AL772190, AL845485, AL845492, AL845515, CU207293
      Consensus CDS
      CCDS50492.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:398489
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    5. NM_001110232.2NP_001103702.1  CUGBP Elav-like family member 2 isoform 5

      See identical proteins and their annotated locations for NP_001103702.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences cause translation initiation at a downstream AUG and an isoform (5) that is shorter than isoform 1.
      Source sequence(s)
      AL772190, AL845485, AL845492, AL845515, CU207293
      Consensus CDS
      CCDS50491.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Related
      ENSMUSP00000002176.6, ENSMUST00000002176.13
      Conserved Domains (3) summary
      cd12638
      Location:392483
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    6. NM_001160292.2NP_001153764.1  CUGBP Elav-like family member 2 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and has multiple differences in the presence and absence of exons at its 5' end and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (7) has a distinct N-terminus, lacks an internal segment, and is shorter than isoform 1.
      Source sequence(s)
      AL772190, AL845492, AL845515
      Consensus CDS
      CCDS59632.1
      UniProtKB/TrEMBL
      S4R1S7, S4R2U7
      Related
      ENSMUSP00000138355.2, ENSMUST00000183209.8
      Conserved Domains (4) summary
      TIGR01661
      Location:54467
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cl17169
      Location:431471
      RRM_SF; RNA recognition motif (RRM) superfamily
    7. NM_001160293.1NP_001153765.1  CUGBP Elav-like family member 2 isoform 1

      See identical proteins and their annotated locations for NP_001153765.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 3' UTR, compared to variant 1. Both variants 1 and 8 encode the same isoform (1).
      Source sequence(s)
      AL845515, BC026856, BC033049, CF536042
      Consensus CDS
      CCDS50494.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Related
      ENSMUSP00000110574.4, ENSMUST00000114924.10
      Conserved Domains (3) summary
      cd12638
      Location:434525
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:57140
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:149229
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    8. NM_001310447.1NP_001297376.1  CUGBP Elav-like family member 2 isoform 8

      See identical proteins and their annotated locations for NP_001297376.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region and lacks an exon in the 3' coding region, compared to variant 1. The resulting isoform (8) is shorter than isoform 1.
      Source sequence(s)
      AK152628, AL845515, BC033049, BY773515
      Consensus CDS
      CCDS79729.1
      UniProtKB/TrEMBL
      A0A0R4J2B0, S4R2U7
      Related
      ENSMUSP00000138359.2, ENSMUST00000182879.8
      Conserved Domains (4) summary
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      TIGR01661
      Location:18435
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:399439
      RRM_SF; RNA recognition motif (RRM) superfamily
    9. NM_001347094.1NP_001334023.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      Consensus CDS
      CCDS84468.1
      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Related
      ENSMUSP00000138297.2, ENSMUST00000150624.9
      Conserved Domains (3) summary
      cd12638
      Location:396487
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    10. NM_001406833.1NP_001393762.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845485, AL845492, AL845515, CU207293
    11. NM_001406834.1NP_001393763.1  CUGBP Elav-like family member 2 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845485, AL845492, AL845515, CU207293
    12. NM_001406835.1NP_001393764.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845485, AL845492, AL845515, CU207293
    13. NM_001406841.1NP_001393770.1  CUGBP Elav-like family member 2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    14. NM_001406842.1NP_001393771.1  CUGBP Elav-like family member 2 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    15. NM_001406843.1NP_001393772.1  CUGBP Elav-like family member 2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
      UniProtKB/TrEMBL
      S4R1S7
    16. NM_001406844.1NP_001393773.1  CUGBP Elav-like family member 2 isoform 38

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    17. NM_001406845.1NP_001393774.1  CUGBP Elav-like family member 2 isoform 36

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    18. NM_001406846.1NP_001393775.1  CUGBP Elav-like family member 2 isoform 37

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    19. NM_001406847.1NP_001393776.1  CUGBP Elav-like family member 2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AL772190, AL845492, AL845515
    20. NM_001406848.1NP_001393777.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      Related
      ENSMUSP00000120459.3, ENSMUST00000142941.8
    21. NM_001406849.1NP_001393778.1  CUGBP Elav-like family member 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    22. NM_001406850.1NP_001393779.1  CUGBP Elav-like family member 2 isoform 37

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    23. NM_001406851.1NP_001393780.1  CUGBP Elav-like family member 2 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    24. NM_001406852.1NP_001393781.1  CUGBP Elav-like family member 2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    25. NM_001406854.1NP_001393783.1  CUGBP Elav-like family member 2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    26. NM_001406855.1NP_001393784.1  CUGBP Elav-like family member 2 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    27. NM_001406858.1NP_001393787.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    28. NM_001406917.1NP_001393846.1  CUGBP Elav-like family member 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      UniProtKB/TrEMBL
      E9QA47
    29. NM_001406918.1NP_001393847.1  CUGBP Elav-like family member 2 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    30. NM_001406919.1NP_001393848.1  CUGBP Elav-like family member 2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    31. NM_001406920.1NP_001393849.1  CUGBP Elav-like family member 2 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    32. NM_001406921.1NP_001393850.1  CUGBP Elav-like family member 2 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    33. NM_001406922.1NP_001393851.1  CUGBP Elav-like family member 2 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    34. NM_001406923.1NP_001393852.1  CUGBP Elav-like family member 2 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    35. NM_001406924.1NP_001393853.1  CUGBP Elav-like family member 2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    36. NM_001406925.1NP_001393854.1  CUGBP Elav-like family member 2 isoform 36

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    37. NM_001406926.1NP_001393855.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    38. NM_001406927.1NP_001393856.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    39. NM_001406928.1NP_001393857.1  CUGBP Elav-like family member 2 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    40. NM_001406929.1NP_001393858.1  CUGBP Elav-like family member 2 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    41. NM_001406930.1NP_001393859.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    42. NM_001406931.1NP_001393860.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    43. NM_001406932.1NP_001393861.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    44. NM_001406933.1NP_001393862.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    45. NM_001406934.1NP_001393863.1  CUGBP Elav-like family member 2 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    46. NM_001406942.1NP_001393871.1  CUGBP Elav-like family member 2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    47. NM_001406943.1NP_001393872.1  CUGBP Elav-like family member 2 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    48. NM_001406944.1NP_001393873.1  CUGBP Elav-like family member 2 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    49. NM_001406945.1NP_001393874.1  CUGBP Elav-like family member 2 isoform 33

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    50. NM_001406946.1NP_001393875.1  CUGBP Elav-like family member 2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    51. NM_001406947.1NP_001393876.1  CUGBP Elav-like family member 2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    52. NM_001406948.1NP_001393877.1  CUGBP Elav-like family member 2 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      UniProtKB/TrEMBL
      A0AAA9WVX7
    53. NM_001406949.1NP_001393878.1  CUGBP Elav-like family member 2 isoform 35

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    54. NM_001406950.1NP_001393879.1  CUGBP Elav-like family member 2 isoform 29

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    55. NM_001406951.1NP_001393880.1  CUGBP Elav-like family member 2 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      UniProtKB/TrEMBL
      A0AAA9WVX7
      Related
      ENSMUSP00000159840.1, ENSMUST00000249661.1
    56. NM_001406952.1NP_001393881.1  CUGBP Elav-like family member 2 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      Conserved Domains (3) summary
      cd12638
      Location:429520
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:46129
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:138218
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    57. NM_001406953.1NP_001393882.1  CUGBP Elav-like family member 2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    58. NM_001406954.1NP_001393883.1  CUGBP Elav-like family member 2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    59. NM_001406955.1NP_001393884.1  CUGBP Elav-like family member 2 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    60. NM_001406956.1NP_001393885.1  CUGBP Elav-like family member 2 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    61. NM_001406957.1NP_001393886.1  CUGBP Elav-like family member 2 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    62. NM_001406958.1NP_001393887.1  CUGBP Elav-like family member 2 isoform 36

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    63. NM_001406959.1NP_001393888.1  CUGBP Elav-like family member 2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    64. NM_001406960.1NP_001393889.1  CUGBP Elav-like family member 2 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      Conserved Domains (3) summary
      cd12638
      Location:429520
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:46129
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:138218
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    65. NM_001406961.1NP_001393890.1  CUGBP Elav-like family member 2 isoform 29

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    66. NM_001406962.1NP_001393891.1  CUGBP Elav-like family member 2 isoform 34

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    67. NM_001406963.1NP_001393892.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    68. NM_001406964.1NP_001393893.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    69. NM_001406965.1NP_001393894.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    70. NM_001406966.1NP_001393895.1  CUGBP Elav-like family member 2 isoform 37

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    71. NM_001406967.1NP_001393896.1  CUGBP Elav-like family member 2 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    72. NM_001406968.1NP_001393897.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    73. NM_001406969.1NP_001393898.1  CUGBP Elav-like family member 2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
      UniProtKB/TrEMBL
      A0A0R4J2B0
    74. NM_001406970.1NP_001393899.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    75. NM_001406971.1NP_001393900.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    76. NM_001406972.1NP_001393901.1  CUGBP Elav-like family member 2 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    77. NM_001406973.1NP_001393902.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515, AL929240
    78. NM_001406974.1NP_001393903.1  CUGBP Elav-like family member 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    79. NM_001406975.1NP_001393904.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    80. NM_001406976.1NP_001393905.1  CUGBP Elav-like family member 2 isoform 37

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    81. NM_001406977.1NP_001393906.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    82. NM_001406978.1NP_001393907.1  CUGBP Elav-like family member 2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
      UniProtKB/TrEMBL
      A0A0R4J2B0
    83. NM_001406979.1NP_001393908.1  CUGBP Elav-like family member 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
      Related
      ENSMUSP00000110577.2, ENSMUST00000114927.9
    84. NM_001406980.1NP_001393909.1  CUGBP Elav-like family member 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
      Related
      ENSMUSP00000097996.5, ENSMUST00000100429.11
    85. NM_001406981.1NP_001393910.1  CUGBP Elav-like family member 2 isoform 32

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    86. NM_001406982.1NP_001393911.1  CUGBP Elav-like family member 2 isoform 33

      Status: VALIDATED

      Source sequence(s)
      AL845492, AL845515
    87. NM_010160.2NP_034290.2  CUGBP Elav-like family member 2 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 3' UTR and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.
      Source sequence(s)
      AK135166, AK164914, AL845515, BY145030, BY495559, CF536042
      Consensus CDS
      CCDS50493.1
      UniProtKB/TrEMBL
      E9QA47, S4R2U7
      Related
      ENSMUSP00000130829.2, ENSMUST00000170438.8
      Conserved Domains (4) summary
      TIGR01661
      Location:60473
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12631
      Location:57140
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:149229
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cl17169
      Location:437477
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      6544505..7401345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011238953.4XP_011237255.1  CUGBP Elav-like family member 2 isoform X12

      See identical proteins and their annotated locations for XP_011237255.1

      Conserved Domains (3) summary
      cd12638
      Location:402493
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    2. XM_036158239.1XP_036014132.1  CUGBP Elav-like family member 2 isoform X12

      Conserved Domains (3) summary
      cd12638
      Location:402493
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:1598
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    3. XM_036158238.1XP_036014131.1  CUGBP Elav-like family member 2 isoform X9

      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:428519
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    4. XM_036158232.1XP_036014125.1  CUGBP Elav-like family member 2 isoform X6

      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:434525
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    5. XM_036158246.1XP_036014139.1  CUGBP Elav-like family member 2 isoform X17

      UniProtKB/TrEMBL
      S4R2U7
      Conserved Domains (4) summary
      TIGR01661
      Location:54471
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cl17169
      Location:435475
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. XM_036158235.1XP_036014128.1  CUGBP Elav-like family member 2 isoform X7

      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:432523
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    7. XM_006497335.5XP_006497398.1  CUGBP Elav-like family member 2 isoform X4

      Conserved Domains (3) summary
      cd12631
      Location:51134
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:143223
      RRM2_CELF1_2; RNA recognition motif 2 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12638
      Location:438529
      RRM3_CELF1_2; RNA recognition motif 3 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    8. XM_006497334.4XP_006497397.1  CUGBP Elav-like family member 2 isoform X2

      See identical proteins and their annotated locations for XP_006497397.1

      UniProtKB/Swiss-Prot
      A2AS10, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z0H4, Q9Z187
      Conserved Domains (3) summary
      cd12638
      Location:440531
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:57140
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:149229
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    9. XM_030247364.1XP_030103224.1  CUGBP Elav-like family member 2 isoform X26

      Conserved Domains (2) summary
      cd12638
      Location:188279
      RRM3_CELF1_2; RNA recognition motif 3 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      TIGR01661
      Location:88275
      ELAV_HUD_SF; ELAV/HuD family splicing factor

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_183219.1: Suppressed sequence

      Description
      NM_183219.1: This RefSeq was suppressed because it appears to represent 3'UTR with an unsupported predicted protein.