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    TTLL15 Tubulin tyrosine ligase-like 15 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41300, updated on 2-Nov-2024

    Summary

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    Official Symbol
    TTLL15provided by FlyBase
    Official Full Name
    Tubulin tyrosine ligase-like 15provided by FlyBase
    Primary source
    FLYBASE:FBgn0037838
    Locus tag
    Dmel_CG4089
    See related
    AllianceGenome:FB:FBgn0037838
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4089; DmCG4089; Dmel\CG4089
    Summary
    Predicted to enable tubulin-glutamic acid ligase activity. Predicted to be involved in protein modification process. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic ventral epidermis; embryonic/larval posterior spiracle; and gut section. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See TTLL15 in Genome Data Viewer
    Location:
    86C7-86C7; 3-50 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10815288..10817490)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6641010..6643212)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cadherin 86C Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Janke C, et al. Science, 2005 Jun 17. PMID 15890843
    2. Towards comprehensive annotation of Drosophila melanogaster enzymes in FlyBase. Garapati PV, et al. Database (Oxford), 2019 Jan 1. PMID 30689844, Free PMC Article
    3. Time-resolved mapping of genetic interactions to model rewiring of signaling pathways. Heigwer F, et al. Elife, 2018 Dec 28. PMID 30592458, Free PMC Article
    4. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables tubulin-glutamic acid ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein modification process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tubulin tyrosine ligase-like 15
    Names
    CG4089-PA
    TTLL15-PA
    NP_650021.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      10815288..10817490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141764.4 → NP_650021.1  tubulin tyrosine ligase-like 15 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650021.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGW2
      Related
      FBpp0081758
      Conserved Domains (1) summary
      pfam03133
      Location:134 → 395
      TTL; Tubulin-tyrosine ligase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGW2 Q9VGW2

    Gene LinkOut

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