U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GIT2 GIT ArfGAP 2 [ Gallus gallus (chicken) ]

    Gene ID: 374035, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Symbol
    GIT2provided by CGNC
    Full Name
    GIT ArfGAP 2provided by CGNC
    Primary source
    CGNC:3839
    See related
    Ensembl:ENSGALG00010021783
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GIT2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6873316..6895991, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6883811..6906511, complement)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene glycolipid transfer protein Neighboring gene trichoplein keratin filament binding Neighboring gene ankyrin repeat domain 13A Neighboring gene uncharacterized LOC107051594

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Analysis of the subcellular distribution of avian p95-APP2, an ARF-GAP orthologous to mammalian paxillin kinase linker. Paris S, et al. Int J Biochem Cell Biol, 2002 Jul. PMID 11950598
    2. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. Turner CE, et al. J Cell Biol, 1999 May 17. PMID 10330411, Free PMC Article
    3. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ARF GTPase-activating protein GIT2
    Names
    G protein-coupled receptor kinase interactor 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395909.1 → NP_001382838.1  ARF GTPase-activating protein GIT2

      Status: VALIDATED

      Source sequence(s)
      AF134571, BU405099, CN383239, CO419884
      UniProtKB/TrEMBL
      Q9DE64, Q9Y621
      Related
      ENSGALP00010031896.1, ENSGALT00010052990.1
      Conserved Domains (6) summary
      sd00045
      Location:137 → 165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1 → 111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:266 → 294
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:634 → 750
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137 → 229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:414 → 478
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6873316..6895991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6883811..6906511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_204206.1: Suppressed sequence

      Description
      NM_204206.1: This RefSeq was removed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.