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    Calm4 calmodulin 4 [ Mus musculus (house mouse) ]

    Gene ID: 80796, updated on 2-Nov-2024

    Summary

    Official Symbol
    Calm4provided by MGI
    Official Full Name
    calmodulin 4provided by MGI
    Primary source
    MGI:MGI:1931464
    See related
    Ensembl:ENSMUSG00000033765 AllianceGenome:MGI:1931464
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DD112; Scarf; 2310037J09Rik
    Summary
    Enables calcium ion binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; bladder; rib; skin; and thymus. Orthologous to human CALML5 (calmodulin like 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Calm4 in Genome Data Viewer
    Location:
    13 A1; 13 2.15 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (3887757..3888671)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (3837757..3838671)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene calmodulin-like 3 Neighboring gene predicted gene, 40655 Neighboring gene calmodulin 5 Neighboring gene STARR-seq mESC enhancer starr_33494 Neighboring gene neuroepithelial cell transforming gene 1 Neighboring gene STARR-positive B cell enhancer ABC_E9391 Neighboring gene STARR-positive B cell enhancer ABC_E7198

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables enzyme regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calmodulin-4
    Names
    calcium binding gene, DD112
    calcium-binding protein Dd112
    skin calmodulin-related factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020036.4NP_064420.2  calmodulin-4

      See identical proteins and their annotated locations for NP_064420.2

      Status: VALIDATED

      Source sequence(s)
      AI131917, AK009956
      Consensus CDS
      CCDS26215.1
      UniProtKB/Swiss-Prot
      Q9CR31, Q9D1E9, Q9JM83
      Related
      ENSMUSP00000041636.5, ENSMUST00000042219.6
      Conserved Domains (2) summary
      PTZ00184
      Location:1148
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:1273
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      3887757..3888671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)