U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Iglv1 immunoglobulin lambda variable 1 [ Mus musculus (house mouse) ]

    Gene ID: 16142, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Iglv1provided by MGI
    Official Full Name
    immunoglobulin lambda variable 1provided by MGI
    Primary source
    MGI:MGI:96530
    See related
    Ensembl:ENSMUSG00000076934 IMGT/GENE-DB:IGLV1; AllianceGenome:MGI:96530
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Igl-V1; 1810027O01Rik
    Summary
    Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. Orthologous to human IGLV7-43 (immunoglobulin lambda variable 7-43); IGLV7-46 (immunoglobulin lambda variable 7-46); and IGLV8-61 (immunoglobulin lambda variable 8-61). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Iglv1 in Genome Data Viewer
    Location:
    16 A3; 16 11.82 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (18903767..18904210, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (19085017..19085460, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda chain complex Neighboring gene STARR-positive B cell enhancer mm9_chr16:19067426-19067726 Neighboring gene STARR-seq mESC enhancer starr_40294 Neighboring gene immunoglobulin lambda joining 3 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr16:19088162-19088462 Neighboring gene immunoglobulin lambda joining 3 Neighboring gene uncharacterized LOC105246083 Neighboring gene STARR-positive B cell enhancer mm9_chr16:19152545-19152846 Neighboring gene U2 small nuclear ribonucleoprotein B pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. Krebber A, et al. J Immunol Methods, 1997 Feb 14. PMID 9032408
    2. Mouse lambda-chain sequences. Cesari IM, et al. Proc Natl Acad Sci U S A, 1973 Jul. PMID 4516208, Free PMC Article
    3. Amino acid and nucleotide sequences of variable regions of mouse immunoglobulin light chains of the lambda 3-subtype. Reilly EB, et al. J Immunol, 1984 Jul. PMID 6202790
    4. Reactivity and structure of a mouse anti-F(ab')2 IgM. Comparison of its variable region sequences with those of a structurally close polyreactive natural IgM. Adib-Conquy M, et al. Mol Immunol, 1994 May. PMID 8190131
    5. Variable region sequence and characterization of monoclonal antibodies to a N,N',N"-trisubstituted guanidine high potency sweetener. Anchin JM, et al. Mol Immunol, 1993 Nov. PMID 8232332

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Other Names

    • A6 anti-[4-hydroxy-3-nitrophenyl(phenolate form)] acetyl mAb V-L region
    • immunoglobulin lambda chain, variable 1
    • immunoglobulin lambda-chain
    • imunoglobulin light chain variable region
    • light chain variable region

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_004051.1 

      Range
      175885..176328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      18903767..18904210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_023499.1: Suppressed sequence

      Description
      NM_023499.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials