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    kdm6a.S lysine demethylase 6A S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 446609, updated on 18-Sep-2024

    Summary

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    Official Symbol
    kdm6a.S
    Official Full Name
    lysine demethylase 6A S homeolog
    Primary source
    Xenbase:XB-GENE-960319
    Locus tag
    XELAEV_18014726mg
    See related
    EnsemblRapid:ENSXLAG00005025336
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    utx; uty; tutx; kdm6a; xtutx
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    Genomic context

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    See kdm6a.S in Genome Data Viewer
    Location:
    chromosome: 2S
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (47825148..47912228, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (44983620..45071133, complement)

    Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121400520 Neighboring gene DNA-dependent metalloprotease SPRTN-like Neighboring gene FUN14 domain containing 1 S homeolog Neighboring gene EF-hand domain containing 2 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC82191

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3K27me2/H3K27me3 demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within heart development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    lysine demethylase 6A S homeolog
    Names
    lysine (K)-specific demethylase 6A S homeolog
    ubiquitously transcribed tetratricopeptide repeat gene, Y-linked

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001093305.1 → NP_001086774.1  lysine demethylase 6A S homeolog

      See identical proteins and their annotated locations for NP_001086774.1

      Status: PROVISIONAL

      Source sequence(s)
      BC077424
      UniProtKB/TrEMBL
      A0A974HV92, Q6AZS3
      Related
      ENSXLAP00005075561.1, ENSXLAT00005077139.1
      Conserved Domains (8) summary
      pfam02373
      Location:1187 → 1295
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:1153 → 1217
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:37 → 317
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      pfam09606
      Location:385 → 835
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      sd00006
      Location:287 → 314
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:320 → 353
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:319 → 380
      TPR_11; TPR repeat
      pfam13431
      Location:274 → 305
      TPR_17; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      47825148..47912228 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018248327.2 → XP_018103816.1  lysine demethylase 6A S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0UIB7, A0A974HV92
      Related
      ENSXLAP00005075707.1, ENSXLAT00005077287.1

    2. XM_018248328.2 → XP_018103817.1  lysine demethylase 6A S homeolog isoform X2

      UniProtKB/TrEMBL
      A0A8J0UL61, A0A974HV92
      Related
      ENSXLAP00005075873.1, ENSXLAT00005077453.1
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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