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    magi1.S membrane associated guanylate kinase, WW and PDZ domain containing 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100158449, updated on 17-Aug-2024

    Summary

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    Official Symbol
    magi1.S
    Official Full Name
    membrane associated guanylate kinase, WW and PDZ domain containing 1 S homeolog
    Primary source
    Xenbase:XB-GENE-6252730
    Locus tag
    XELAEV_18026015mg
    See related
    EnsemblRapid:ENSXLAG00005002756
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    aip3; bap1; wwp3; magi1; baiap1; magi-1; tnrc19
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    Genomic context

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    See magi1.S in Genome Data Viewer
    Location:
    chromosome: 4S
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (123394128..123695006)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (117152791..117265772)

    Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene leucine-rich repeats and immunoglobulin like domains 1 S homeolog Neighboring gene transfer RNA threonine (anticodon UGU) Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 9 S homeolog Neighboring gene prickle planar cell polarity protein 2 S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      123394128..123695006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041561777.1 → XP_041417711.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J1KK75, A0A974D0N8
      Conserved Domains (6) summary
      smart00228
      Location:1107 → 1191
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1280 → 1452
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:953 → 1048
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. XM_041561779.1 → XP_041417713.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8J1KLV2, A0A974D0N8
      Conserved Domains (6) summary
      smart00228
      Location:1095 → 1179
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1268 → 1440
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:953 → 1036
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    3. XM_041561778.1 → XP_041417712.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8J1KK68, A0A974D0N8
      Related
      ENSXLAP00005008286.1, ENSXLAT00005008412.1
      Conserved Domains (6) summary
      smart00228
      Location:1106 → 1190
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1279 → 1451
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:952 → 1047
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    4. XM_041561780.1 → XP_041417714.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8J1KN95, A0A974D0N8
      Related
      ENSXLAP00005008263.1, ENSXLAT00005008388.1
      Conserved Domains (6) summary
      smart00228
      Location:1094 → 1178
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1267 → 1439
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:952 → 1035
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    5. XM_041561781.1 → XP_041417715.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8J1KK71, A0A974D0N8
      Related
      ENSXLAP00005008282.1, ENSXLAT00005008408.1
      Conserved Domains (6) summary
      smart00228
      Location:1094 → 1178
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1267 → 1439
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:940 → 1035
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    6. XM_041561782.1 → XP_041417716.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8J1KK80
      Conserved Domains (5) summary
      smart00228
      Location:1107 → 1191
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:953 → 1048
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    7. XM_041561786.1 → XP_041417720.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8J1KK76
      Related
      ENSXLAP00005008277.1, ENSXLAT00005008403.1
      Conserved Domains (5) summary
      smart00228
      Location:1106 → 1190
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:952 → 1047
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    8. XM_041561787.1 → XP_041417721.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A8J1KK85
      Conserved Domains (5) summary
      smart00228
      Location:1094 → 1178
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:940 → 1035
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    9. XM_041561785.1 → XP_041417719.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A8J1KNA0
      Related
      ENSXLAP00005008235.1, ENSXLAT00005008361.1
      Conserved Domains (5) summary
      smart00228
      Location:1107 → 1191
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:223 → 335
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00201
      Location:302 → 331
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:953 → 1048
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:116 → 190
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    10. XM_041561784.1 → XP_041417718.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8J1KLV6, A0A974D7A2
      Conserved Domains (5) summary
      smart00228
      Location:873 → 957
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:2 → 114
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1046 → 1218
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:81 → 110
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:719 → 814
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    11. XM_041561783.1 → XP_041417717.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8J1KK74, A0A974D7A2
      Conserved Domains (5) summary
      smart00228
      Location:886 → 970
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG5021
      Location:2 → 114
      HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      PRK12678
      Location:1059 → 1231
      PRK12678; transcription termination factor Rho; Provisional
      cd00201
      Location:81 → 110
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:732 → 827
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    Nucleotide Protein Strain
    Heading Accession and Version

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