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    mig30.L mig30 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398291, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mig30.L
    Official Full Name
    mig30 L homeolog
    Primary source
    Xenbase:XB-GENE-6251788
    Locus tag
    XELAEV_18003703mg
    See related
    EnsemblRapid:ENSXLAG00005005892
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    mig30
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    Genomic context

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    See mig30.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (350314..352944, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694845.1 (965289..969524, complement)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene matrix metalloproteinase 21 like L homeolog Neighboring gene T cell leukemia, homeobox 2 L homeolog Neighboring gene polycomb group ring finger 1 L homeolog Neighboring gene transcription factor LBX2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of the secreted factor Mig30 expressed in the Spemann organizer impairs morphogenetic movements during Xenopus gastrulation. Hayata T, et al. Mech Dev, 2002 Mar. PMID 11850177
    2. Expression analysis of IGFBP-rP10, IGFBP-like and Mig30 in early Xenopus development. Kuerner KM, et al. Dev Dyn, 2006 Oct. PMID 16894599
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables insulin-like growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell growth IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in interstitial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kazal-type serine protease inhibitor domain-containing protein 1; mig30 L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      350314..352944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041586414.1 → XP_041442348.1  kazal-type serine protease inhibitor domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      Q0N3X3, Q8QFQ2
      Related
      ENSXLAP00005017584.1, ENSXLAT00005017879.1
      Conserved Domains (4) summary
      smart00280
      Location:113 → 147
      KAZAL; Kazal type serine protease inhibitors
      pfam00219
      Location:37 → 92
      IGFBP; Insulin-like growth factor binding protein
      cd00096
      Location:159 → 163
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:151 → 249
      Ig; Immunoglobulin domain

    2. XM_041586405.1 → XP_041442339.1  kazal-type serine protease inhibitor domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      B7ZQT4, Q0N3X3
      Conserved Domains (4) summary
      smart00280
      Location:113 → 147
      KAZAL; Kazal type serine protease inhibitors
      pfam00219
      Location:37 → 92
      IGFBP; Insulin-like growth factor binding protein
      cd00096
      Location:159 → 163
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:151 → 249
      Ig; Immunoglobulin domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001088737.1: Suppressed sequence

      Description
      NM_001088737.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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