terf2.L telomeric repeat binding factor 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: terf2.L
Official Full Name: telomeric repeat binding factor 2 L homeolog
Primary source: Xenbase:XB-GENE-990302
Locus tag: XELAEV_18022625mg
See related: EnsemblRapid:ENSXLAG00005025987
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: trf2; terf2
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 4L

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (55069345..55086447, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (49856669..49873816, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables G-rich strand telomeric DNA binding	IEA Inferred from Electronic Annotation more info
enables double-stranded telomeric DNA binding	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info
enables telomerase activity	IEA Inferred from Electronic Annotation more info
enables telomeric DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of telomere maintenance via recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of telomeric D-loop disassembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protection from non-homologous end joining at telomere	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein localization to chromosome, telomeric region	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of telomere maintenance via telomerase	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within telomere maintenance	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within telomeric D-loop disassembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within telomeric loop formation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome, telomeric region	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of shelterin complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: telomeric repeat binding factor 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095697.1 → NP_001089166.1 telomeric repeat binding factor 2 L homeolog

See identical proteins and their annotated locations for NP_001089166.1

Status: PROVISIONAL

Source sequence(s)

DQ118429

UniProtKB/TrEMBL

A0A974D3K8, B8QB41, Q1WM12

Related

ENSXLAP00005077299.1, ENSXLAT00005078890.1

Conserved Domains (4) summary

smart00717
Location:412 → 461

SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

cd11660
Location:413 → 461

SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family

pfam16772
Location:251 → 288

TERF2_RBM; Telomeric repeat-binding factor 2 Rap1-binding motif

cl02779
Location:19 → 212

TRFH; Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability, ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

55069345..55086447 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)