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    lmnb1.L lamin B1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 379745, updated on 18-Sep-2024

    Summary

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    Official Symbol
    lmnb1.L
    Official Full Name
    lamin B1 L homeolog
    Primary source
    Xenbase:XB-GENE-489662
    Locus tag
    XELAEV_18007951mg
    See related
    EnsemblRapid:ENSXLAG00005035110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    lmnb1; lamin-b; Lamin-L(I)
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    Genomic context

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    See lmnb1.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (182620038..182641609, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (169469959..169491631, complement)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 10 L homeolog Neighboring gene membrane associated ring-CH-type finger 3 L homeolog Neighboring gene phosphorylated adaptor for RNA export L homeolog Neighboring gene aldehyde dehydrogenase 7 family member A1 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly. Goodman B, et al. J Biol Chem, 2010 Nov 5. PMID 20826821, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly.
      Title: Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • MGC52550

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within heterochromatin formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nuclear envelope organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nuclear migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nuclear pore localization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein localization to nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear lamina IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    lamin B1 L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001086584.1 → NP_001080053.1  lamin B1 L homeolog

      See identical proteins and their annotated locations for NP_001080053.1

      Status: PROVISIONAL

      Source sequence(s)
      BC041185
      UniProtKB/TrEMBL
      A0A974E1P6, O93398, Q8AVZ3
      Related
      ENSXLAP00005105096.1, ENSXLAT00005107140.1
      Conserved Domains (2) summary
      pfam00038
      Location:31 → 387
      Filament; Intermediate filament protein
      pfam00932
      Location:435 → 543
      LTD; Lamin Tail Domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      182620038..182641609 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials