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    pole2.L polymerase (DNA directed), epsilon 2, accessory subunit L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 399116, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pole2.L
    Official Full Name
    polymerase (DNA directed), epsilon 2, accessory subunit L homeolog
    Primary source
    Xenbase:XB-GENE-973819
    Locus tag
    XELAEV_18039628mg
    See related
    EnsemblRapid:ENSXLAG00005018774
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    pole2
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    Genomic context

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    See pole2.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (84069502..84084916)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (69382162..69397575)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene salvador family WW domain containing protein 1 L homeolog Neighboring gene nuclear export mediator factor L homeolog Neighboring gene kelch domain containing 2 L homeolog Neighboring gene kelch domain containing 1 L homeolog Neighboring gene dynein, axonemal, assembly factor 2 L homeolog Neighboring gene mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. Waga S, et al. Proc Natl Acad Sci U S A, 2001 Apr 24. PMID 11296256, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA-templated DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within error-prone translesion synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of epsilon DNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed DNA polymerase epsilon 2
    Names
    DNA polymerase epsilon subunit B
    polymerase (DNA directed), epsilon 2 (p59 subunit)
    NP_001083783.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001090314.1 → NP_001083783.1  DNA-directed DNA polymerase epsilon 2

      See identical proteins and their annotated locations for NP_001083783.1

      Status: PROVISIONAL

      Source sequence(s)
      AB048257
      UniProtKB/TrEMBL
      A0A974H840, Q9DGB4
      Related
      ENSXLAP00005055438.1, ENSXLAT00005056643.1
      Conserved Domains (2) summary
      pfam04042
      Location:288 → 488
      DNA_pol_E_B; DNA polymerase alpha/epsilon subunit B
      pfam12213
      Location:3 → 73
      Dpoe2NT; DNA polymerases epsilon N terminal

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      84069502..84084916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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