U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cpsf2.S cleavage and polyadenylation specific factor 2 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 394394, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cpsf2.S
    Official Full Name
    cleavage and polyadenylation specific factor 2 S homeolog
    Primary source
    Xenbase:XB-GENE-950598
    Locus tag
    XELAEV_18041315mg
    See related
    EnsemblRapid:ENSXLAG00005011743
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    cpsf2; cpsf2-A
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cpsf2.S in Genome Data Viewer
    Location:
    chromosome: 8S
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (21048808..21069337, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (20964066..20985023, complement)

    Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 3 S homeolog Neighboring gene uncharacterized LOC108699821 Neighboring gene solute carrier family 24 member 4 S homeolog Neighboring gene NADH:ubiquinone oxidoreductase subunit B1 S homeolog Neighboring gene ataxin 3 S homeolog Neighboring gene fibulin 5 S homeolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The cleavage and polyadenylation specificity factor in Xenopus laevis oocytes is a cytoplasmic factor involved in regulated polyadenylation. Dickson KS, et al. Mol Cell Biol, 1999 Aug. PMID 10409759, Free PMC Article
    2. Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation. Barnard DC, et al. Cell, 2004 Nov 24. PMID 15550246
    3. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA 3'-end processing by stem-loop binding and cleavage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mRNA cleavage and polyadenylation specificity factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mRNA cleavage and polyadenylation specificity factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cleavage and polyadenylation specificity factor subunit 2
    Names
    CPSF 100 kDa subunit
    cleavage and polyadenylation specific factor 2, 100kDa
    cleavage and polyadenylation specificity factor 100 kDa subunit

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087654.1 → NP_001081123.1  cleavage and polyadenylation specificity factor subunit 2

      See identical proteins and their annotated locations for NP_001081123.1

      Status: PROVISIONAL

      Source sequence(s)
      AF139986
      UniProtKB/Swiss-Prot
      Q9W799
      UniProtKB/TrEMBL
      A0A974H4X8
      Related
      ENSXLAP00005034282.1, ENSXLAT00005035165.1
      Conserved Domains (5) summary
      smart01027
      Location:243 → 368
      Beta-Casp; Beta-Casp domain
      COG1236
      Location:5 → 388
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      pfam07521
      Location:527 → 566
      RMMBL; RNA-metabolizing metallo-beta-lactamase
      pfam13299
      Location:608 → 780
      CPSF100_C; Cleavage and polyadenylation factor 2 C-terminal
      cd16293
      Location:7 → 204
      CPSF2-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 2 and related proteins; MBL-fold metallo-hydrolase domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      21048808..21069337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041574122.1 → XP_041430056.1  cleavage and polyadenylation specificity factor subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8J1LLC5, A0A974H4X8
      Conserved Domains (2) summary
      smart01027
      Location:243 → 368
      Beta-Casp; Beta-Casp domain
      cd16293
      Location:7 → 204
      CPSF2-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 2 and related proteins; MBL-fold metallo-hydrolase domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W799.1 GenPept UniProtKB/Swiss-Prot:Q9W799

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials