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    tmpo.S thymopoietin S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 397975, updated on 4-Nov-2024

    Summary

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    Official Symbol
    tmpo.S
    Official Full Name
    thymopoietin S homeolog
    Primary source
    Xenbase:XB-GENE-865826
    Locus tag
    XELAEV_18021275mg
    See related
    EnsemblRapid:ENSXLAG00005014845 AllianceGenome:Xenbase:XB-GENE-865826
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    lap2; tmpo; xlap2
    Summary
    Predicted to enable DNA binding activity. Predicted to be located in membrane and nuclear envelope. Orthologous to human TMPO (thymopoietin). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tmpo.S in Genome Data Viewer
    Location:
    chromosome: 3S
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (95753727..95767158, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (93930627..93944155, complement)

    Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA53 Neighboring gene small nucleolar RNA SNORA53 Neighboring gene solute carrier family 25 member 3 S homeolog Neighboring gene dynein heavy chain 3, axonemal-like Neighboring gene NEDD1 gamma-tubulin ring complex targeting factor S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization and developmentally regulated expression of Xenopus lamina-associated polypeptide 2 (XLAP2). Lang C, et al. J Cell Sci, 1999 Mar. PMID 9973608
    2. Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility. Iioka H, et al. Nat Cell Biol, 2007 Jul. PMID 17558393
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC132163

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    thymopoietin S homeolog
    Names
    lamina associated polypeptide 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001088178.1 → NP_001081647.1  thymopoietin S homeolog

      See identical proteins and their annotated locations for NP_001081647.1

      Status: PROVISIONAL

      Source sequence(s)
      Y17861
      UniProtKB/TrEMBL
      A0A974D8K4, Q9YGK9
      Related
      ENSXLAP00005043445.1, ENSXLAT00005044516.1
      Conserved Domains (2) summary
      cd12940
      Location:93 → 134
      LEM_LAP2_LEMD1; LEM (Lap2/Emerin/Man1) domain found in lamina-associated polypeptide 2 (LAP2), LEM domain-containing protein 1 (LEMP-1) and similar proteins
      pfam08198
      Location:2 → 49
      Thymopoietin; Thymopoietin protein

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      95753727..95767158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018254131.2 → XP_018109620.1  thymopoietin S homeolog isoform X4

      UniProtKB/TrEMBL
      A0A8J0UXM7

    2. XM_018254129.2 → XP_018109618.1  thymopoietin S homeolog isoform X2

      UniProtKB/TrEMBL
      A0A8J0UT43, A0A974D8K4

    3. XM_018254130.2 → XP_018109619.1  thymopoietin S homeolog isoform X3

      UniProtKB/TrEMBL
      A0A8J0UUB6, A0A974D8K4
      Related
      ENSXLAP00005043462.1, ENSXLAT00005044533.1

    4. XM_018254128.2 → XP_018109617.1  thymopoietin S homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0UMB0, A0A974D8K4
      Related
      ENSXLAP00005043457.1, ENSXLAT00005044528.1

    RNA

    1. XR_001934962.2 RNA Sequence

      Related
      ENSXLAT00005044536.1
    Nucleotide Protein Strain
    Heading Accession and Version

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