xpo1.S exportin 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: xpo1.S
Official Full Name: exportin 1 S homeolog
Primary source: Xenbase:XB-GENE-993244
Locus tag: XELAEV_18028477mg
See related: EnsemblRapid:ENSXLAG00005016409
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: Xpo; crm1; xpo1; exportin-1
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 5S

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5S	NC_054380.1 (1002405..1035279, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5S	NC_030733.1 (1004293..1037196, complement)

Chromosome 5S - NC_054380.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRM1 binds to Axin in the presence of RanGTP
Title: Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables nuclear export signal receptor activity	IEA Inferred from Electronic Annotation more info
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein export from nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ribosomal large subunit export from nucleus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ribosomal small subunit export from nucleus	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: exportin 1 S homeolog

Names: CRM1/XPO1 protein; exportin 1 (CRM1 homolog)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090265.1 → NP_001083734.1 exportin 1 S homeolog

See identical proteins and their annotated locations for NP_001083734.1

Status: PROVISIONAL

Source sequence(s)

BC070550

UniProtKB/TrEMBL

A0A974CPW3, Q6NS03, Q9PW90

Related

ENSXLAP00005048351.1, ENSXLAT00005049466.1

Conserved Domains (4) summary

smart00913
Location:46 → 112

IBN_N; Importin-beta N-terminal domain

smart01102
Location:709 → 1027

CRM1_C; CRM1 C terminal

COG5101
Location:15 → 1044

CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]

pfam08389
Location:123 → 268

Xpo1; Exportin 1-like protein