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    Prr27 proline rich 27 [ Mus musculus (house mouse) ]

    Gene ID: 73779, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Prr27provided by MGI
    Official Full Name
    proline rich 27provided by MGI
    Primary source
    MGI:MGI:1921029
    See related
    Ensembl:ENSMUSG00000002240 AllianceGenome:MGI:1921029
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930432K09Rik
    Summary
    Is expressed in craniocervical region bone; lung; and male reproductive gland or organ. Orthologous to human PRR27 (proline rich 27). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 64.4) See more
    Orthologs
    human all
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    Genomic context

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    See Prr27 in Genome Data Viewer
    Location:
    5 E1; 5 43.56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (87973556..87994245)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (87825697..87846386)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene casein alpha s2-like A Neighboring gene casein alpha s2-like B Neighboring gene STARR-seq mESC enhancer starr_13564 Neighboring gene DAZ interacting protein 1 pseudogene Neighboring gene odontogenic, ameloblast asssociated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Rijnkels M, et al. Genomics, 2003 Oct. PMID 13679022
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC118299

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 27

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163551.1 → NP_001157023.1  proline-rich protein 27 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001157023.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC074046, AK015291, BY446468, BY714849
      Consensus CDS
      CCDS51535.1
      UniProtKB/TrEMBL
      Q3SYJ2, Q9D5J3
      Related
      ENSMUSP00000098617.2, ENSMUST00000101056.8
      Conserved Domains (1) summary
      PRK14951
      Location:183 → 320
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    2. NM_028648.3 → NP_082924.2  proline-rich protein 27 isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, which results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK015291, BY446468, BY714849
      Consensus CDS
      CCDS39134.1
      UniProtKB/TrEMBL
      E9Q591, Q9D5J3
      Related
      ENSMUSP00000002310.7, ENSMUST00000002310.8
      Conserved Domains (1) summary
      PRK14951
      Location:175 → 312
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      87973556..87994245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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