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    Chst13 carbohydrate sulfotransferase 13 [ Mus musculus (house mouse) ]

    Gene ID: 71797, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Chst13provided by MGI
    Official Full Name
    carbohydrate sulfotransferase 13provided by MGI
    Primary source
    MGI:MGI:1919047
    See related
    Ensembl:ENSMUSG00000056643 AllianceGenome:MGI:1919047
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C4ST-3; 1110067M19Rik
    Summary
    Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity and chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and skeleton. Orthologous to human CHST13 (carbohydrate sulfotransferase 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver adult (RPKM 13.9), placenta adult (RPKM 12.7) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Chst13 in Genome Data Viewer
    Location:
    6 D1; 6 40.13 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (90285333..90302167, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (90308351..90325185, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 54 Neighboring gene cDNA sequence BC048671 Neighboring gene urocanase domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E10392 Neighboring gene STARR-seq mESC enhancer starr_16614 Neighboring gene ZXD family zinc finger C Neighboring gene STARR-seq mESC enhancer starr_16615

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance. Akita K, et al. Stem Cells, 2008 Mar. PMID 18079434
    2. Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells. Schaberg E, et al. Front Cell Dev Biol, 2021. PMID 34169071, Free PMC Article
    3. Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. van der Zwaag B, et al. Genomics, 2005 Jul. PMID 15953540
    4. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-acetylgalactosamine 4-O-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables chondroitin 4-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chondroitin sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    carbohydrate sulfotransferase 13
    Names
    carbohydrate (chondroitin 4) sulfotransferase 13
    NP_082204.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027928.1 → NP_082204.1  carbohydrate sulfotransferase 13 precursor

      Status: VALIDATED

      Source sequence(s)
      AC122521
      Consensus CDS
      CCDS51847.1
      UniProtKB/TrEMBL
      D3Z6E3
      Related
      ENSMUSP00000064897.5, ENSMUST00000070890.6
      Conserved Domains (1) summary
      pfam03567
      Location:99 → 327
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      90285333..90302167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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