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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_007259.1 RefSeqGene
- Range
-
4868..100494
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_47
mRNA and Protein(s)
-
NM_000186.4 → NP_000177.2 complement factor H isoform a precursor
See identical proteins and their annotated locations for NP_000177.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
- Source sequence(s)
-
AL049744, BC142699, BM842566, BP324193, Y00716
- Consensus CDS
-
CCDS1385.1
- UniProtKB/Swiss-Prot
- A5PL14, P08603, P78435, Q14570, Q2TAZ5, Q38G77, Q5TFM3, Q8N708, Q9NU86
- Related
- ENSP00000356399.4, ENST00000367429.9
- Conserved Domains (4) summary
-
- cd00033
Location:1109 → 1163
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- smart00032
Location:146 → 205
- CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
- PHA02927
Location:10 → 262
- PHA02927; secreted complement-binding protein; Provisional
- pfam00084
Location:811 → 864
- Sushi; Sushi repeat (SCR repeat)
-
NM_001014975.3 → NP_001014975.1 complement factor H isoform b precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) utilizes an alternate terminal exon which results in an early stop codon. The resulting protein (isoform b, also known as the "factor H-like 1" or "FHL-1" isoform) has a distinct C-terminus and is shorter than isoform a.
- Source sequence(s)
-
AL049744, BC073982, BM842566
- Consensus CDS
-
CCDS53452.1
- UniProtKB/TrEMBL
- A0A0D9SG88, A0A8Q3WM71
- Related
- ENSP00000487250.1, ENST00000630130.2
- Conserved Domains (4) summary
-
- cd00033
Location:85 → 142
- CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
- smart00032
Location:146 → 205
- CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
- PHA02927
Location:10 → 262
- PHA02927; secreted complement-binding protein; Provisional
- pfam00084
Location:325 → 384
- Sushi; Sushi repeat (SCR repeat)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
196652043..196747504
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 PATCHES
Genomic
-
NW_025791754.1 Reference GRCh38.p14 PATCHES
- Range
-
501706..597238
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
195998386..196093925
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)