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    SRP14-DT SRP14 divergent transcript [ Homo sapiens (human) ]

    Gene ID: 100131089, updated on 22-Oct-2024

    Summary

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    Official Symbol
    SRP14-DTprovided by HGNC
    Official Full Name
    SRP14 divergent transcriptprovided by HGNC
    Primary source
    HGNC:HGNC:48619
    See related
    Ensembl:ENSG00000248508 AllianceGenome:HGNC:48619
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SRP14-AS1
    Expression
    Ubiquitous expression in thyroid (RPKM 1.7), heart (RPKM 1.6) and 25 other tissues See more
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    Genomic context

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    See SRP14-DT in Genome Data Viewer
    Location:
    15q15.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (40039311..40067509)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (37844581..37874346)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40331512..40359710)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40251723-40252224 Neighboring gene H3 histone pseudogene 38 Neighboring gene Sharpr-MPRA regulatory region 10520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40314575-40315076 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40315077-40315576 Neighboring gene uncharacterized LOC124903471 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:40330400-40331345 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:40331346-40332290 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9222 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9223 Neighboring gene signal recognition particle 14 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40347031-40347610 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9226 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40354716-40355551 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9227 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9228 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:40360521-40360704 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6316 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9229 Neighboring gene uncharacterized LOC105370787 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40369263-40369763 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40374533-40375217 Neighboring gene VISTA enhancer hs1611 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9231 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40389627-40390140 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6317 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40395438-40396002 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40396003-40396568 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:40397101-40397293 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9233 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9234 Neighboring gene Sharpr-MPRA regulatory region 12469 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40399683-40400378 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6318 Neighboring gene Bcl2 modifying factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. Postel-Vinay S, et al. Nat Genet, 2012 Feb 12. PMID 22327514
    2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Comuzzie AG, et al. PLoS One, 2012. PMID 23251661, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • SRP14 antisense RNA1 (head to head)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_040059.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC021755, AC025168, AI424388, AK127696, EB388563

    2. NR_040060.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon and uses an alternate splice site, compared to variant 1.
      Source sequence(s)
      AC021755, AC025168, AI424388, AK127696
      Related
      ENST00000504245.9

    3. NR_040061.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two exons, includes two alternate exons and uses an alternate splice site, compared to variant 1.
      Source sequence(s)
      AC025168, AK127696, BM706250, BU737016
      Related
      ENST00000560341.3

    4. NR_040062.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two exons, includes an alternate exon and uses an alternate splice site, compared to variant 1.
      Source sequence(s)
      AC025168, AK127696, BX111264
      Related
      ENST00000746697.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      40039311..40067509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      37844581..37874346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials