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    nup88 nucleoporin 88 [ Danio rerio (zebrafish) ]

    Gene ID: 321744, updated on 12-Sep-2024

    Summary

    Official Symbol
    nup88provided by ZNC
    Official Full Name
    nucleoporin 88provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-297
    See related
    Ensembl:ENSDARG00000003235 AllianceGenome:ZFIN:ZDB-GENE-050522-297
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb16f10; wu:fb33e09; zgc:112439; ik:tdsubc_2f7; xx:tdsubc_2f7
    Summary
    Predicted to be a structural constituent of nuclear pore. Predicted to act upstream of or within mRNA transport; protein transport; and ribosomal subunit export from nucleus. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Is expressed in several structures, including brain; eye; immature eye; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in fetal akinesia deformation sequence syndrome 4. Orthologous to human NUP88 (nucleoporin 88). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See nup88 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (59089699..59111962, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58419990..58442253, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene rabaptin, RAB GTPase binding effector protein 1 Neighboring gene VPS37D subunit of ESCRT-I Neighboring gene PRKR interacting protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nucleocytoplasmic transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within ribosomal large subunit export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within ribosomal small subunit export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleoporin 88
    Names
    nuclear pore complex protein Nup88

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020466.1NP_001018302.1  nucleoporin 88

      See identical proteins and their annotated locations for NP_001018302.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095815
      UniProtKB/Swiss-Prot
      A0A2R8QUY6, A2CEI4, Q501Y6
      Related
      ENSDARP00000025718.7, ENSDART00000023123.8
      Conserved Domains (1) summary
      pfam10168
      Location:8719
      Nup88; Nuclear pore component

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      59089699..59111962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394619.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      75305..95231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)